Uses Of Peptides

Peptides are short polymers of amino acid monomers joined by peptide bonds. They are distinguished from proteins based on their size, typically containing less than 50 monomer units. A peptide is formed by the union of two or more amino acids. When the number of amino acid is less than about 50 of these molecules are called peptides while larger sequences are known as proteins. The amino acids are coupled by a peptide bond, a special link in which the nitrogen atom of one amino acid joins to the carboxyl carbon atom of another.

The peptides are present in all living cells and have a variety of biochemical activities. Appear as enzymes, hormones, antibiotics, receivers, etc. peptide synthesis is performed by coupling the C-terminal carboxyl of an amino acid with the N-terminal amino group or other group or.

Peptides play a crucial role in fundamental physiological and biochemical functions of life. For decades, the peptide research has grown as a field of science. They have recently received prominence in molecular biology for several reasons. The first is to allow the creation of antibodies in animals without the need to purify the protein of interest. This involves synthesis of antigenic peptides of sections of the protein of interest; These are then used to produce antibodies against rabbit or mouse protein. Other reasons interest has recently grown peptides is that they have become instrumental in mass spectrometry, allowing the identification of proteins of interest based on peptide mass and sequence; in this case, they are most often generated by digestion gel after electrophoretic separation of proteins.

The peptides have recently been used to study the structure and function of proteins. For example, synthetic peptides can be used as probes for protein-peptide where interactions occur. Inhibitor also they used in clinical research to examine the effects of that in inhibiting proteins of cancer and other diseases.

As interest in peptides has grown, so too have the techniques for making and studying new applications for it. For example, the library is a recently developed technique for study related protein. A library containing a large number of those systematic combination of amino acids; providing a powerful tool for drug design, protein-protein interactions, and other biochemical and pharmaceutical applications.

Interest in peptides is likely to continue in the future. The number of peptides that enter clinical trials are likely to grow, and the use of conjugated peptides carbohydrates, antibodies and other proteins are likely to become more frequent. The peptides not only be used as the active ingredient of the new drugs, but as "addiction" to other pharmaceutical agents. In addition, the range of medical indications grow that peptides address. Peptide-based substances continue to find commercial use. Almost certainly more peptides find use for the treatment of obesity, metabolic syndrome and type 2 diabetes Peptides also be used to treat the symptoms and diseases that currently can not be treated with medication.

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