How Stem cell Treatment For Autism Improves The Mental And Immune Functions
ASD or Autism Spectrum Disorders are a group of neurodevelopment conditions whose incidences are now attaining epidemic rates. One out of every 166 children suffers from ASD. Stem cell therapy can provide relief to patients who suffer from the disease.
Autism is the most common kind of ASD affecting children worldwide. The disease characterizes itself by impaired non-verbal and verbal communication, abnormalities in carrying out social interactions and obsessive and repetitive behavior. Autism is caused by both genetic as well as environmental factors. Children who suffer Autism are withdrawn and appear self-occupied.
Lower Blood Circulation and Hypoxia
Children who suffer from autism have subnormal or impaired CNS circulation and hypoxia (lower oxygen supply). Hypoperfusion (shock) affects brain areas that are responsible for Autism. For instance, hypoxia and shock in the temporal lobe portion of the brain may cause defects in social interactions, face-recognition, and language comprehension. Damage to other areas of the brain like the hippocampus, amygdala, and the temporal areas cause lowering of eye contact, unexpressive faces, and motor stereotype occurrence. Cell death may also be affecting the children.
Ischemia or inadequacy of blood supply to the Autism affected areas of the brain can be overcome therapeutic angiogenesis or by the induction of new human blood vessels. Angiogenesis can also provide for neurological recovery. Stem cell treatment can increase angiogenesis. Hence, stem cell treatment for autism can deal effectively with ischemia and hypoxia.
Immune Dysregulation Affecting Autistic Children
The human nervous system and the immune system share the characteristic of non-self and self-regulation, memory, and specificity among other characteristics and functions. The immune system enjoys bi-directional communication with the neural system. Autism not only affects the brain areas, but it also causes dysfunctionalities within the immune system. Autistic children suffer from the hyperactivity of astrocytes, cells that carry out and mediate several inflammatory and immunological effects. When astrocytes oversecrete the inflammatory agents, then a number of neurological diseases may occur. The hyper-activated astrocytes also secrete neurotoxic substances that cause neural damage. Autistic children also suffer from the abnormalities related to the T and B cells that are an integral part of the immune system.
Mesenchymal Stem Cells or MSCs are a kind of pluripotent that are found in blood, bone marrow, and dermis, among other body areas. The MSCs secrete certain immune inhibition factors. As Autistic patients suffer from a hyperactive immune system, this property of MSCs can provide relief to them.
Stem cells can repair the damaged tissues at the functional, molecular and structural level. They can differentiate to form specialized cells and can also secrete certain substances that aid the repair of the damaged neurons. Stem cell therapy for autism and the rehabilitative program support and complement each other to improve the life of Autistic children.,
Stem cell therapy improves the quality of life of patients in a number of areas. Post stem cell therapy the patients show improvements in areas like:
- Improvement of eye to eye contact
- Reduction in aggressive and self-stimulatory behavior
- Improvement in social interactions in communication skills
- Better motor activities and increased sensory functionality
Rehabilitation
Only the best of stem cell therapy providers and institutes (like NeuroGen Brain and Spine Institute) offer a comprehensive rehabilitation program for improving the mental and physical aspects of patients in multiple ways. The components of the rehabilitation program include Physiotherapy, Neuro-Rehab Facility, Speech Therapy, Psychologist Counseling Sessions, Aquatic Therapy, Orthopedic Surgeons, Urologist Treatment, Dance and Music Therapy, Diet Counseling, Yoga Therapy and Motivational Workshops.
The different therapies improve the speech, muscle strength, movements and other mental and physical health defects of patients suffering from autism. The holistic approach improves the life of autistic patients in multiple ways.