Natural Killer Cells Market Research Report with Analysis and Forecasts to 2026
Natural killer cells are a form of granular lymphocytes of varying sizes that play an important role in innate immunity in the human body. They typically constitute of around 10% of total blood lymphocytes as compared to around 70% and 20% of T cells and B cells, respectively. Natural killer cells are cytotoxic in nature and are able to kill their targets cells by two different mechanisms: as antibody dependent cell-mediated cytotoxicity (ADCC) and as simple natural killer activity of these cells. Furthermore, lectin-like receptors are one of two complex families of membrane receptors that recognize carbohydrates expressed on all cells. Such receptor engages its ligand when a natural killer cell encounters any normal cell that leads to generation of signal triggered, which in turn stimulates the natural killer cells to carry out its process. Though natural killer cells are demonstrated to be critical elements in the early immune response to a large variety of intracellular pathogens, they are used in clinical applications for treating lymphomas and other disorders. This in turn is expected to favor growth of the natural killer cells market over the forecast period (2016–2024).
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Keen focus of various organizations towards immuno-oncology to fuel growth of the natural killer cells market over the forecast period:
The global natural killer cells market is highly competitive and fragmented, though companies are investing of specific therapy using natural killer cell products to be used in immune-oncology to treat cancer and other tumors. Major players in the market are developing novel products and spending significantly in research and development to expand their product portfolio. Major players in the market of natural killer cells include NantKwest, NKT Therapeutics Inc, AvidBiotics, Glycostem, Sorrento Therapeutics, Inc., CellGenix GmbH, Lonza and R&D Systems, Inc.
Application of the cells in treatment of critical diseases is expected to favor growth of the natural killer cells market:
Natural killer cells play an important role in stem-cell transplantation in therapies involving such cells activating endogenous natural killer cells and may transfer exogenous cells through adoptive cell therapy (ACT) and hematopoietic stem cell transplantation (HSCT). According to National Center for Biotechnology Information, U.S. National Library of Medicine, in 2014, such therapies are less effective in eliminating cancer stem cells as revealed by various studies.
Major players in the natural killer cells market are engaged in research and development process and offer a large product portfolio. For instance, R&D Systems offer a wide range of reagents for culturing natural killer cells and investigating natural killer cell and tumor cell interactions and various other components such as recombinant proteins, blocking/neutralization antibodies, fluorochrome-conjugated antibodies and ELISA Kits.
Natural Killer Cells Market Taxonomy:
By Product Type:
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Kits
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Reagents
By Application:
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AIDS
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Malignant and Non-Malignant Cancer
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Immunotherapy
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Stem Cell Transplantation
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