NGS Sample Preparation Market Growth Analysis, Development Strategies & Advancement Technologies

Author: Swati Bis

Next-generation sequencing (NGS) provides sequence profiling from transcriptomes and genome to deoxyribonucleic acid (DNA)-protein interactions. The technologies used in the workflow of sequencing are an integral part of research and discovery in biology. The capability to produce the maximum number of sequence data in a relatively short time provides a broader range of applications and accelerates advances in research studies hospitals and clinics, which has transformed understanding of human health, diagnosis, and treatment of diseases. NGS sample preparation workflows are part of the diagnosis of disease biomarkers. Moreover, the field of genomics has significantly positioned itself as a hotspot of academic scientific research and clinical medicine. Technological developments, such as precision medicine, next-generation sequencing (NGS), and RNA-sequencing have made significant advances in science and technology and simultaneously opened avenues for public healthcare.

The global NGS sample preparation market is projected to reach $3,279.3 million by 2026, growing from $1,468.9 million in 2020, at a CAGR of 14.24% during the forecast period 2021-2026.

Growth in this market is expected to be driven by the increasing use of NGS for genetic disorders, technological advancements in NGS sample preparation, and rising research fundings in the field of genomics. However, factors such as high cost and automated NGS sample preparation instruments, dearth of skilled professionals, and lack of expertise are some of the significant challenges restraining the growth of the global NGS sample preparation market.

Market Footprint and Growth Potential

The global NGS sample preparation market has witnessed moderate growth, owing to the increasing demand for non-invasive biopsy procedures for the early detection and treatment of cancer. This improves the quality of life and reduces the time of treatment.

The continued significant investments by healthcare companies to meet the industry demand and the growing adoption of NGS technology among healthcare professionals are the major factors propelling the growth of the NGS sample preparation market.

The COVID-19 pandemic upended the world as everyone knows it, taking a terrible toll in terms of lives lost and impact on businesses, education, personal life, and just about every aspect of society. To support customers and help them overcome their obstacles during the year, the companies managed through the many aspects of a challenging environment, rapidly changing market conditions, the ins and outs of government lockdowns, adjustments in the way the people work, and the personal and professional challenges facing our team members.

Market Drivers Technological Advancements in NGS Sample Preparation Methods

Technological advancements in the field of genetic analysis and testing have the potential to foster growth in the market. Companies are launching products with new technologies and expanding their footprints to consolidate their presence to cater to the growing demand for NGS.Companies dealing in diagnostic and screening instrumentation are changing their focus to develop technologically advanced automated systems which could provide efficient and error-free results in a limited time frame. The amalgamation of automation with medical diagnostics and screening has opened new opportunities in the field of genomics research. The kit developed by different companies also helps to detect cancer mutations. Hence, this successful innovation of NGS sample preparation products offered by the key industry players is likely to enhance diagnostic and research results, thereby providing quality results.

Market RestraintsHigh Cost of Automated NGS Sample Preparation Instruments

Next-generation sequencing and RNA-sequencing are expensive procedures. To conduct these methods, certain processes are considered that involve DNA or RNA isolation, library preparation, and sequencing reagents, data analysis, and storage. To undergo such research, it is required to have skilled professionals who are trained in handling such techniques as it requires proper maintenance. Thus, the lack of clarity about NGS sample preparation research and high maintenance costs are limiting the spread of technical knowledge about this market.

Market OpportunitiesAdoption of Automated NGS Sample Preparation in the Emerging Markets

Improvements in diagnostic methods for the diagnosis of genetic and chronic diseases are highly prioritized all across the globe. There are lots of advancements pertaining to the effective diagnosis of genetic diseases; however, there remains a lack of adoption of technologically advanced equipment in emerging economies. Most of the developing economies in the world still opt for manual instruments in the field of research and diagnostics on account of financial feasibility. This has led to a hurdle in adopting automated systems, thereby hindering the efficiency and accuracy in the field of research and diagnostics. With the increasing prevalence of chronic and genetic diseases in emerging markets, the need for automated equipment like NGS is rising. Additionally, emerging markets hold a massive scope for the adoption of automated NGS sample preparation in the field of diagnostics, which could bolster revenue generation, thereby positively contributing to the market growth.

Key Questions Answered in this Report:
  • How is NGS sample preparation revolutionizing oncology?
  • What are the major market drivers, challenges, and opportunities in the global NGS sample preparation market?
  • What are the underlying structures resulting in the emerging trends within the global NGS sample preparation market?
  • How is the COVID-19 pandemic impacting the global NGS sample preparation ecosystem?
  • What are the key development strategies that are being implemented by the major players in order to sustain themselves in the competitive market?
  • What are the key regulatory implications in developed and developing regions pertaining to the use of NGS sample preparation products?
  • What are the potential entry barriers expected to be faced by the companies willing to enter a particular region?
  • How is each segment of the market expected to grow during the forecast period 2021-2026, and what is the anticipated revenue to be generated by each of the segments? Following are the segments:
  • Product (Consumables, Standalone Automation Instruments, Automated Workstation, Accessories and Components)
  • Workflow (Library Preparation, Target Enrichment, Sample Extraction/Isolation, Fragmentation, Sample Quantification, Library Quantification, Quality Control (QC), and Pooling)
  • Application (DNA Sequencing, Whole Genome Sequencing, RNA Sequencing, Methylation Sequencing, and Others)
  • Therapeutic Area (Oncology, Infectious Diseases, Human Genetics/Population Genetics, and Others)
  • End User (Hospitals and Clinics, Academic and Research Institutions, Pharmaceutical and Biotechnology Companies, and Others)
  • Region (North America, Europe, Asia-Pacific, Latin America, and Rest-of-the-World)
  • What are the growth opportunities for the NGS sample preparation companies in the region of their operation?
  • Who are the leading players with significant offerings in the global NGS sample preparation market?
  • Which companies are anticipated to be highly disruptive in the future, and why?

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