Vasculitis: Symptoms, Causes, Types, and Treatments Vasculitis is a group of rare but serious medic

Vasculitis is one of the uncommon but serious medical conditions characterized by inflammation of blood vessels. It can cause severe destruction to the blood vessels and can cause a variety different symptoms, and even complications.

This is a brief overview that will help you understand the complexities of this disease, along with its symptoms, causes that cause it, the causes and treatments.

What is vasculitis?

Vasculitis is an medical term used to describe swelling of blood vessels. In essence, it is an autoimmune disease that affects all parts that is a part of the system for vascular which includes veins, arteries and capillaries. It leads to the growth of the walls around blood vessels, the narrowing of vessels and can cause blood flow to be impaired. Vasculitis is commonly described as angiitis, or arteritis.

Symptoms of Vasculitis

The signs and symptoms of vasculitis can differ significantly depending on the blood vessels affected as well as their location and the level of inflammation. The most frequent symptoms are:

Persistent fatigue

Flu-like and fever-like symptoms

Skin changes, like ulcers, rashes, or red or discoloration of the skin (purpura)

Joint and muscle pain

Neuropathy can cause Numbness, tingling, and the weakness in the extremities

Vision changes, for example the blurred or reddened vision and eye discomfort

Issues with the heart and respiratory system like shortness of breath or chest discomfort.

Intestinal symptoms, like diarrhea, abdominal pain and bleeding

Reflux symptoms, like kidney dysfunction, and in severe instances kidney failure

Other organs are involved like those of the central nervous systems the gastrointestinal tract, and the muscle skeletal system

Vasculitis types

Vasculitis can be classified into various kinds based on a variety of parameters, including the size of blood vessels that are affected and the organs affected and the root causes. Here are the most common kinds of vasculitis:

Large Vessel Vasculitis

Giant Cell Arteritis (GCA)

The most common cause is those with large blood vessels, and in particular the temporal arteries

The cause of headaches as well as jaw pain, scalp tenderness and vision issues, such as loss of vision.

Takayasu Arteritis

It is primarily concerned with the aorta and its main branches

Could cause in diminished blood flow to various areas of the body.

Symptoms: fatigue, muscle pain, organ damage (severe cases)

Medium Vessel Vasculitis

Polyarteritis Nodosa (PAN)

The most common cause is that it affects the medium-sized arteries.

The condition is defined by that there are immune complexes in the blood vessels of patients

Signs and symptoms: muscles pain, skin lesions and nerve damage. abdominal pain

Small Vessel Vasculitis

Granulomatosis and Polyangiitis (GPA)

It can cause respiratory problems, sinusitis and kidney damage

Other signs: may include eye inflammation and skin eruptions

Eosinophilic Granulomatosis and polyangiitis (EGPA)

It is often associated with asthma, vasculitis and allergic rhinitis.

Can impact multiple organ systems

Microscopic Polyangiitis (MPA)

The results in kidney issues or lung issues. Also, skin eruptions

Usually, this is due to the presence of cytoplasmic anti-neutrophil antibodies (ANCAs)

Other Types of Vasculitis

Hypersensitivity vasculitis can be caused by the occurrence of an allergy reaction medicines or infections, as well as other external triggers

The vasculitis of the immune system is defined by that it has immune complexes in the blood vessels which cause inflammation and damages

Anti-Neutrophil Cytoplasmic (ANCA)-Associated Vasculitis comprises GPA as well as MPA. It is frequently caused by inflammation in the kidneys, respiratory tract, as well as other organs.

Behcet's disease predominantly affects blood vessels in different parts in the human body. It is well-known for its tendency to cause chronic or genital and oral ulcers and eye inflammation.

Cryoglobulinemic vasculitis is caused by cryoglobulins in the blood. These are an abnormal protein that can cause an immune complex and inflammation. It can result in problems with joints, skin and other organs.

IgA Vasculitis (Henoch-Schonlein Purpura) typically affects children and young adults. It is defined by an itch on the skin (purpura) and joint pain, digestive symptoms, and kidney involvement.

Kawasaki Disease affects small children. This causes a the swelling in their small and large blood vessels. It can possibly cause inflammation in coronary blood vessels. It can also lead to the swelling in lymph nodes (glands) and mucous membranes that line the nose, eyes and mouth.

Buerger's disease is also known as thromboangiitis or obliterans creates blockages in the blood vessels. This results in decreasing the flow of blood to various parts of the body. It also causes damage to the skin. It is most often seen in feet, but can cause problems to the small veins in the legs and arms. Gangrene is the biggest and most destructive result.

The causes of vasculitis

The most common triggers and factors that are associated with vasculitis are:

Family heritage

Infections, like Hepatitis B and Hepatitis C

Certain kinds of leukemia.

Hypersensitive reaction to specific types of drugs, which includes certain antibiotics and anti-seizure medicines.

The underlying medical condition include rheumatoidarthritis or Lupus

Treatment for vasculitis

Vasculitis generally requires an all-disciplinary team of healthcare specialists, such as rheumatologists Pulmonologists, and nephrologists to provide comprehensive care. Below is the list of most common treatment options:

Corticosteroids, like prednisone

Anti-inflammatory drugs, like methotrexate and azathioprine as well as Cyclophosphamide

Biologic drugs, like tocilizumab and rituximab

Plasma exchange (Plasmapheresis) may be recommended in the most severe of cases to eliminate harmful immune complexes and antibodies from bloodstream.

Control of cholesterol and blood pressure medicines

Treatment for symptoms may be recommended in cases of multiple organs being affected and needing an additional treatment

Lifestyle changes that include regular exercise and a balanced diet and a cessation of smoking (especially in the case of Buerger disease)

Vasculitis treatment using stem cells

Stem cell therapy exploits the immune-modulatory and regeneration capabilities of the stem cell. At Plexus we utilize stem cells to repair or replace damaged blood vessels and ultimately reduce inflammation and speed up your body's process of healing. We make use of mesenchymal autologous stem cells (MSCs) sourced from the patient's body in order to alleviate discomfort and to avoid any further damage to blood vessels.

The treatment of stem cells at Plexus can help patients suffering from vasculitis in the following ways:

Regeneration of tissues damaged by injury

Normal blood flow and less inflammation

Immunomodulation

Reduction in dependence on immunosuppressive medications

Stem cells treatmentis revolutionary method to address the root cause of vasculitis, decrease inflammation and enhance your quality of life of patients. To learn more about our individualized Regenerative Rehabilitation to treat vasculitis get in touch with Team Plexus today.

WhatsApp +91 89048 42087

Call +91 78159 64668 (Hyderabad) | +91 82299 99888 (Bangalore)

FAQsWhat is the most effective treatment for vasculitis?

Stem cells therapy offers a new sense of possibility to people suffering from vasculitis.

What type of disease is vasculitis?

It is an extremely serious inflammation.

What is the primary source of vasculitis?

The root reason for vasculitis is not known. However, studies suggest that it may be caused by any one or a combination of the following factors:

Family heritage

Infections

Certain kinds of autoimmune diseases

Drug reactions

Certain kinds of leukemia.

Who is most susceptible to vasculitis?

Each type of vasculitis is unique and has its own risks, which include the age of the patient or family history, lifestyle choices (smoking) and medications and other autoimmune disorders.