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Unique Monoclonal Canine (Dog) Antibody Production by Creative Biolabs
Posted: Feb 02, 2016
Dogs are the first domesticated animals. They are widely showed as companions in no matter working, hunting or pet. Currently, the number of dogs is between 700 million and one billion, making them the most abundant predators in the world.
As we always said, dogs as the best friends of humans. Therefore, to protect dogs our friends from diseases should be listed in the list of biopharmaceutical research.
Antibody phage display, especially monoclonal antibody phage display, is commonly used in disease treatment and prevention. While, when it comes to monoclonal canine antibody, not much information is offered. Creative Biolabs, however, is an exceptional.
As a leader in the fields of phage display and antibody engineering, Creative Biolabs is specialized in developing monoclonal rabbit, chicken, llama, dog, monkey, mouse and human antibodies with phage display antibody library technology. Particularly, it is the first and the only supplier to provide monoclonal canine antibody generation services.
Based on its extensive experience in phage display library construction and screening, scientists of Creative Biolabs have developed several immunized canine antibody libraries, from which they successfully isolated a number of high affinity antibodies utilizing panning technology. With this strategy, they can generate custom monoclonal canine antibodies which have the potential to function in a wide range of biomedical applications, including the treatment of malignant, infectious, inflammatory and autoimmune diseases in dogs, paving the way for exploration of such applications in canine medicine.
In terms of antigens that are not suitable for immunization, Creative Biolabs can also make a custom synthetic canine antibody library for you based on its full understanding of the canine antibody repertoires. It can take the major framework sequence of light chain heavy chain of canine antibody repertoires, and then create mutations or variations in all 6 CDR regions (or 2 CDR3 regions). Combined with various mutation strategies, Creative Biolabs can produce canine antibodies against any antigens, including those that are toxic and of no immune response in animals.
About Creative Biolabs
Creative Biolabs is specialized in providing custom biotechnology and pharmaceutical services that cover the full scope of biotechnology needs of early antibody drug discovery and development.
I'm Oliver Ray from LA. I'm interested in writing everything about biotechnology. Hope you enjoy reading my articles.