Bispecific Antibody Products and a Series of Related Services by Creative Biolabs

According to wiki, bispecific antibody (BsAb) is an artificial protein that is composed of fragments of two different monoclonal antibodies and consequently binds to two different types of antigen.

Compared with traditional antibodies, bispecific antibodies (BsAbs) have many advantages such as two distinct binding specificities, great potenial for clinical application, the ability to improve immune responses and activate T-lymphocytes. Based on these unique features, BsAbs can be applied in Oncology, Immunology, Hematology, Ophthalmology, Osteology, Pulmonary and respiratory diseases, Diagnostics, Gene therapy, etc. The most widely used application of this approach is in cancer immunotherapy, where BsAbs are engineered that simultaneously bind to a cytotoxic cell (using a receptor like CD3) and a target like a tumour cell to be destroyed.

As a reliable supplier in the field of antibody, Creative Biolabs designs and generates high quality bispecific antibody products. According to customer's detailed requirements, it provides various bispecific antibody construction services utilizing different technological platforms developed by itself.

"Our scientists have extensive experience in engineering antibodies and can offer you specific strategies tailored to your exact needs", introduced Monica Müller, Scientific Officer of Creative Biolabs, "We offer pure and well behaved bispecific antibodies as well as numerous different constructions, including bispecific IgGs, appended IgGs, bispeci?c antibody fragments, bispecific fusion proteins and bispeci?c antibody conjugates"

As Dr Monica introduced, they offer a full range of technological approaches needed for bispecific antibody development.

Genetic Engineering combines the molecular design and recombinant antibody expression techniques to custom BsAbs in multiple formats. Chemical Conjugation utilizes suitable chemical crosslinkers to couple mAbs and antibody fragments. Hybrid–hybridoma Technology generates BsAbs based on the fusion of two different hybridoma cell lines.

In addition to bispecific antibody production, related analyzing services are in urgent need in the antibody market.

With the common efforts of its scientists, Creative Biolabs successfully established various bispecific antibody analytical platforms, and can perform quality assessment, characteristic analysis as well as preclinical research for therapeutic BsAb discovery or manufacturing.

About Creative Biolabs

Creative Biolabs is a US provider specialized in antibody products and services. Its cutting-edge hybridoma development and phage display platforms allow the production of the most comprehensive list of recombinant antibody products, range from antibody / peptide libraries, Biosimilar cell lines, Chimeric antigen receptor (CAR) products, antibody-drug conjugates (ADCs) to engineered antibodies such as therapeutic antibodies, single-domain antibodies, bispecific antibodies and intrabodies.

I'm Oliver Ray from LA. I'm interested in writing everything about biotechnology. Hope you enjoy reading my articles.