The History of X-ray crystallography

In 2014, the X-ray crystallography was alive for 100 years. 100 years ago, in order to reward M. v. Laue, W. H. Bragg and W. L. Bragg for finding X-ray diffraction and X-ray crystallography, they are granted for Nobel Prize in Physics.

In November 8, 1895, W. K. Rontgen found X-ray. The discovery of X-ray marks the birth of modern physics, promoting the creation and development of modern chemistry and modern biology, having an extremely profound influence on the physics field and the whole field of science and technology, having created dozens of Nobel Prize winner in physical science, chemistry, biology, medicine and other related sciences and making an indelible contribution to the development of science. To this end, Roentgen won the first Nobel physics prize in 1901.

Laue showed a keen interest in the natural sciences at a young age. At Strasbourg high school, he and two students repeated the X-ray experiment discovered by Roentgen with the guaid of an enthusiastic teacher.

In April of 1912, Laue the first time placed the film between the copper sulfate crystal and X - ray tubes, but got no results after exposure for a few hours. At second experiment, he put the film in the back of the crystal, and finally observed some thick and oval spots in the film around the vicinity of the transmission spots.

Then Laue's theory of two-dimensional grating diffraction is extended to the three-dimensional grating, and the Laue equation describing the crystal diffraction is obtained.

Less than one month after the publish of X - ray diffraction photos by Laue, the news was spread to the United Kingdom, and W. H.Bragg/W. L. Bragg paid great attention.

Extraordinary scientific analysis ability made them determine which may be focusing crystal reflector. Crystal in neat rows of parallel atomic planes can be as a diffraction grating. Diffraction spots of Laue are the results of the grating reflection X-ray. In October of the same year, the famous Prague equation was derived.

The Prague equation reflects the relationship between the wavelength of X - ray and the crystal plane distance, which can be used to measure the wavelength of X - ray, and can be used as a tool for the phase determination of the crystal structure.

The discovery of the Laue equation and X - ray diffraction, as well as the establishment of Prague equation marks the birth of X ray crystallography.

Creative Biostructure has used technologies like X-ray crystallography, a href=http://www.creative-biostructure.com/epitope-mapping-services-for-linear-and-conformational-epitopes-88.htmepitope mapping...