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Discovering a Drug Against Aging: Target Identification and Validation
Posted: Dec 01, 2016
Translational research and aging
Some diseases sometimes serve as an eye opener to biological processes. The same goes for translational research. The bench to bedside medicine delivery research has shown the impact that certain diseases have on aging. This information has helped the study for the discovery of a drug against aging.
Biomarkers – novel ways to accurately predict capability
For biomarkers to be effective, the study on humans have always been considered ineffective. This is because of the long life of the species. Gerontologists have devised novel biomarkers that can be free from the limitations of the long time required to register changes.
Sirtuins and their effect on anti-aging
Sirtuins have virtually led the charge against aging by showing significant results in tests on mice. The reversal of aging effects and certain deteriorations related to metabolism were witnessed and recorded. This, and other discoveries go on to prove that a drug for aging can indeed be developed in the near future.
The convergence of biotechnology, pharmaceuticals, and information technology will help speed up the process of drug discovery. Genome sequencing and complex algorithms of computing considerably help the search for the best drug. Drug repurposing and personalized medicines together help in narrowing down the search through effective delivery of targeted therapies. The world is closer to understanding the process of aging through senescence and negligible senescence. All of this contributes to the eventual discovery of an anti-aging drug.
I believe that the most important challenges are still of a technological nature. We need to understand the biology of aging better first.
Know more about researches in the field of combating aging at http://gero.com/
This article is written by Julia Ogun, a Public Relations Officer at Gero LLC. Gero is a drug development company based in Moscow, Russia. They are working on creating first in class small molecule therapeutics using proprietary.