Sorafenat 200mg Tablets Buy Online Price in india (Sorafenib 200mg

Sorafenat is the newest drug, a multi-kinase inhibitor with antitumor effect.

The active substance - Sorafenib, has a suppressive effect on tumor growth. Sorafenat is used in the treatment of metastatic renal cell and hepatocellular carcinoma. The conducted studies have established the effectiveness of the drug - Sorafenat is able to reduce the risks of further disease progression with such diagnoses as primary liver cancer or hepatocellular carcinoma. The drug is used in more than 100 countries. The use of Sorafenat is also relevant as a substitute for interferon-alpha and interleukin therapy in those patients who, due to various factors, are not suitable for this treatment or did not help. The use of Sorafenat is also possible as a first-line therapy for inoperable and locally advanced and disseminated kidney cancer, as well as the 2nd line for the treatment of non-cell carcinoma of the kidney and tumors, Sorafenat 200mg Tablets Buy Online Price in India

Directions for use:

Inside. The recommended dose is 800 mg/day. It is possible to take Sorafenat on an empty stomach, and with food. It is desirable that the food does not contain a large amount of fat, as it helps reduce the bioavailability of sorafenib.

Treatment of Sorafenat is discontinued if the clinical effect disappears.

The drug should be discontinued also if an unacceptable toxic effect arises against the background of Sorafenat treatment.

Dose reduction up to 400 mg/day may be required if there are various side effects.

There is no data on the use of Sorafenat in patients with impaired hepatic function and in patients who are on hemodialysis.

Special instructions:

Treatment of Sorafenat is carried out under the supervision of a doctor who has experience of antitumor therapy.

During the entire course of taking Sorafenat, monitoring of peripheral blood counts (leukocyte count and platelets) is required.

Most often, adverse reactions to the administration of Sorafenat were skin reactions, especially in the limbs, and rashes. As a rule, they were the first or second degree of severity, and their manifestation was noted during the first 6 weeks of therapy. Such undesirable reactions can be suppressed by lowering the dose of Sorafenat, the appropriate treatment. With repeated repetition of these side effects, as well as in case of their severe manifestation, treatment with sorafenib cannot be continued.

During the course of taking Sorafenat, you should regularly monitor the patient's blood pressure to prevent the development of hypertension. If necessary, prescribe antihypertensive drugs. With the development of severe or persistent hypertension is possible to cancel the drug.

When prescribing Sorafenat in combination with warfarin, prothrombin time, INR and clinical signs of bleeding should be regularly determined.

For the appointment or resumption of therapy with Sorafenat in the case of surgical interventions requires a special solution, which should be based on an assessment of the adequacy of wound healing.

Therapy with Sorafenat can be stopped when there are signs of ischemia and/or myocardial infarction, perforation of the gastrointestinal tract.

Sorafenat should be used with caution in combination with drugs that are metabolized/withdrawn mainly with the participation of UGT1A1 (irinotecan), as well as with docetaxel.

Patients with a risk of renal dysfunction should monitor the water-electrolyte balance.

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