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Protein A Resin Market projected to grow with significant CAGR over the forecast period

Author: Ram Reddy
by Ram Reddy
Posted: May 07, 2018

Protein A is a surface protein that basically found in cell wall of bacteria Staphylococcus aureus. It has many applications in biopharmaceutical and biochemical industry especially in monoclonal antibodies purification. Protein A resin is a chromatographic medium that is used to analyze and separate the antibodies. Because of its ability to bind immunoglobulins protein A resin is also used in immunological research. Nowadays protein A resins produced mostly using recombinant DNA technology in Escherichia coli.

A wide range of applications in biopharmaceutical industry, increasing biological products manufacturing, increasing use and development of newer technologies for drug purification are expected to grow the market of Protein A resins. In addition to this, advantages over conventional chromatographic separation of antibodies such as high selectivity, improved antibody yield along with ease in large and small scale antibody purification may further drive protein a resins market. However, high-cost of Protein A resin purification method in comparison with conventional chromatographic separation techniques hindering the protein A resin market growth. In addition, development of alternatives for protein A resins such as aqueous two phase separation, mixed mode chromatography and cation exchange may hamper the protein A resins market.

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Global Protein A resin market has been categorized into-

1. Matrix type

  • Glass or Silica
  • Agarose
  • Organic Polymer

2. Applications

  • Antibody Separation
  • Immunoprecipitation

3. End-users

Biopharmaceutical Industries, Clinical Research Laboratories and Academic Institutions.

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And lastly, geographically protein a resin market into following regiosn- North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa. North America dominates the market revenue share among the all regions due to technological advancements, well-established healthcare industry and favorable government policies. In addition, growth of monoclonal antibodies market in U.S. directly contributing to growth of effective antibody purifying techniques and related products & services. Protein A resin market is expected to grow at significant rate in Asia – Pacific region due to shifting the global interest for manufacturing in biopharmaceutical manufacturing capacities in emerging economies of the region like India and China. Europe’s growth in monoclonal antibodies sales may drive the revenue growth of protein A resin market in the region. Some of the key players in protein A resin market are Novasep Holding SAS (Novasep) (U.S.), GE Healthcare (U.S.), Thermo Fisher Scientific Inc. (U.S.), E. Merck KG (Merck KGaA) (Germany), JSR Corporation (Japan), Tosoh Corporation (Japan), Repligen Corporation (U.S.), Expedeon Ltd. (U.S.), and GenScript (U.S.) to name a few. In 2017, Purolite, a chemical manufacturing company collaborated with ChromaTan Corporation to develop a novel protein A bead.

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The key players are investing into Protein A Resin market with the help of R & D to gain the competitive advantage. Geographic expansion, new product development and collaborations are major strategies adopted by the key market players. For instance, in 2016, German life sciences company Atoll acquired by Repligen for $22.5 Mn. This acquisition will expand Repligens chromatography column business and further diversifying its business supply of protein A ligands. Similarly, in 2016, Repligen Corporation has extended a long term supply agreement with GE Healthcare through 2019 for Protein A ligands manufacturing at its facility in Lund, Sweden. Furthermore, in 2011, Novasep, a leading supplier of manufacturing solutions to the life sciences industries, launched of AbSolute High Cap, a new generation Protein A media, based on modified silica.

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Author: Ram Reddy

Ram Reddy

Flag of United Kingdom
United Kingdom

Member since: May 02, 2018
Published articles: 57

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