Global Bioabsorbable Stents Market Research and Forecast 2018-2023

Coronary artery diseases are one of the most prominent causes of death globally. According to the American Heart Association, around 45% of deaths in the U.S. occur due to the coronary heart diseases every year. Drug-eluting stents have been developed for treating weakened or narrowed arteries in the body. It keeps the artery open and assists in the blood supply to the body. However, the drug-eluting stents are made up of metal, which can, therefore, have the ability to destroy the walls of artery. This has augmented the need for the development of bioabsorbable stents in the market. The global bioabsorbable stents market is majorly propelling due to huge investments made by the researchers and the companies for the development of polymer-based stents.

The history of stent began in 1988, where the first biodegradable scaffold was developed by the Duke University in Durham, North Carolina and Thorax center in Rotterdam, the Netherlands. The development of stents has revolutionized the treatment of coronary artery disease by refining immediate and late complications associated with balloon angioplasty. The cardiac stents are developed in the shape of the metal mesh, which cannot be permanently inserted into the artery. However, the next-generation drug eluting stents utilizes polymers that are bioabsorbable, which in turn reduces barriers related to drug-eluting scaffold and thrombosis.

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Bioabsorbable stents are mainly developed from polymers. These are used for the treatment of coronary artery diseases and associated peripheral diseases. The bioabsorbable stents deliver a drug that keeps an artery open, in order to prevent blockage after angioplasty. Unlike coronary stents, the bioabsorbable stents do not stay permanently in the artery, rather resorb within the walls of the blood vessels, when the patient no longer needed it. The scaffold is only needed to place in the artery for around six to twelve months, thereinafter, the tissues around the blockage remodel itself according to the opened passage.

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Bioabsorbable stents are primarily made up of polylactic acid, which is a naturally dissolvable material used in medical implants, including dissolving sutures. The drawbacks of using polymer include recoil after expansion, stent thickness causing maneuverability and crossing issues, difficulty visualizing a non-metallic stent on fluoroscopy and stents not crimping firmly on delivery balloons. Bioabsorbable stents came into the arena to provide several advantages over bare metal stents and drug-eluting stents. These include improved lesion imaging, abolished late stent thrombosis, reduction in revascularization procedures, freedom from side-branch obstruction, restoration of vasomotion, and strut fracture-induced restenosis.

According to the data published by the World Health Organization (WHO), in 2015, around 17.7 million people died from cardiovascular diseases globally, accounting to around 7.4 million deaths due to coronary heart disease. The bioabsorbable stents have greatly used in the interventional cardiology, which presents a novel approach of the stents in the treatment of coronary artery disease. The growth of the global bioabsorbable stents market is mainly associated with the introduction of bioabsorbable stents by the researchers, in order to overcome the drawbacks of metallic drug-eluting stents such as permanent caging of the blood vessel.

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