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Things that You Should Know About Chlorination using Thionyl Chloride

Author: Gunjan Kothia
by Gunjan Kothia
Posted: Sep 07, 2018

Thionyl chloride is an inorganic compound with the chemical, which is a moderately volatile colourless liquid with an unpleasant acrid odour. Thionyl chloride is primarily used as a chlorinating reagent, with approximately 45,000 tonnes per year being produced during the early 1990s.

Whether it is for the production of gangesh group’s largest single product, Diethylaminoethyl Chloride Hydrochloride 869-24-9, or for the manufacture of chlorination reagents and downstream fine chemicals or for custom synthesis, Thionyl Chloride for the chlorination reactions are of central significance to SGR's products.

Why Thionyl chloride is preferred for Chlorination?

Thionyl Chloride is the important intermediate of pharmaceutical industry, which is used for making acyl chloride as well as being used for the manufacture of pharmaceutical intermediates such as Tyramine hydrochloride 60-19-5 and CyclopropaneCarbonyl Chloride 4023-34-1. It can also be used as a dehydrating agent or solvent.

Thionyl chloride has a long shelf life; however "aged" samples develop a yellow hue, possibly due to the formation of disulfur dichloride. Thionyl chloride is susceptible to photolysis, which primarily proceeds via a radical mechanism. Samples showing signs of ageing can be purified by distillation under reduced pressure, to give a colourless liquid.

Reaction of Thionyl chloride

Thionyl chloride is mainly used in the industrial production of organochlorine compounds, which are often intermediates in pharmaceuticals and agrichemicals. It usually is preferred over other reagents, which simplifies purification of the product. Many of the products of thionyl chloride are themselves highly reactive and as such it is involved in a wide range of reactions.

Final Thoughts

Thionyl chloride is a reactive compound that can violently release dangerous gases upon contact with water and other reagents. But the leading pharmaceutical intermediates manufacturer in India, Shree Ganesh Remedies Limited uses the right procedure and propotion for the manufacture of chlorination reagents and downstream fine chemicals.

Also for environmental protection, they always convey chlorination reagents in closed systems. Gaseous secondary products or by-products from the chlorination processes are recycled and or converted into suitable secondary products which can be sold in to market.

The author of this article is the leading manufacture of pharmaceutical intermediates like CyclopropaneCarbonyl Chloride 4023-34-1, Tyramine hydrochloride 60-19-5 and more. In this article, he shared the things that you should know about chlorination using thionyl chloride. To know more, visit http://www.ganesh-group.com/

About the Author

The author of this article is a leading pharmaceutical intermediates manufacturer in India. In this article he discusses the active pharmaceutical ingredients and its benefits. To know more, visit http://www.ganesh-group.com/

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Author: Gunjan Kothia

Gunjan Kothia

Member since: Jul 12, 2018
Published articles: 4

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