Natamycin Market : Analysis and Research Report by Experts 2024

Natamycin Market: Overview

Natamycin is also known commonly as pimaricin or natacyn. It is an anti-fungal agent produced during aerobic fermentation by the Streptomyces natalensis, a bacterium found commonly in soil. Natamycin is a polyene macrolide anti-biotic Natamycin is sparingly soluble in water and required in very low concentrations. available as an odorless, white, granular powder as well as crystalline solid. Commercially, Natamycin can be produced through industrial scale fermentation process with the help of Streptomyces natalensis followed by isolation of the antibiotic either through broth extraction or through seperation of the mycelium.

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The mode of antifungal action of natamycin involves binding to specific receptors on the fungal membranes and is dependent on the presence of sterols in the fungal cell membrane, usually ergosterol. This binding causes leakages in the fungal cell membrane and leads to eventual death of the fungi. Natamycin is mostly used as an additive in food for preservation and protection against growth of fungi such as yeasts and moulds. Natamycin and its broken down metabolite products do not have toxicity for humans or animals. Repeated daily natamycin intakes of more than 500 mg/kg, through cheese or meat, have been found to cause diarrhea, vomiting and nausea in humans.

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Natamycin Market: Application Insight

Natamycin is primarily used as an essential ingredient in packaged foods and beverages, especially in dairy and meat products, for preservation. It is a preferred substitute for traditional chemical preservatives. Potential benefits for the utility of natamycin over chemical preservatives include neutral taste or flavor impact and less pH dependence for efficacy. Natamycin can be utilized in several ways such as aqueous suspensions (brine mixtures) that can be sprayed on the products’ surface or the product can be dipped into the solution. It can also be used in powdered forms (along with certain anti-caking agents including cellulose) that can be sprinkled on and/or mixed into the food product. Natamycin is also used in pharmaceuticals and drugs as antifungal preservatives and in antifungal creams or solutions for skin, eyes or oral infection. Natamycin is not absorbed by the body and does not cause any systemic infections in humans.

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