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Basic Pharma Lifescience Pvt. Ltd. is the leading Chlorhexidine Base Manufacturer

Author: Basic Pharma
by Basic Pharma
Posted: Feb 10, 2019

Chlorhexidine is used along with regular tooth brushing/flossing to treat gingivitis, a gum disease. Chlorhexidine belongs to a class of drugs known as antimicrobials.

It works by decreasing the amount of bacteria in the mouth, helping to reduce swelling that causes redness of the gums and bleeding when you brush.Basic Pharma Lifescience is leading manufacturer of Chlorhexidine and Cetrimide in India. The marketing team attended CPHI India Delhi 2019 to meet the multinational client for international business development.Chlorhexidine CAS 55-56-1 ManufacturerChlorhexidine Base

Chlorhexidine is an antiseptic and disinfectant which is effective against a wide range of vegetative Gram-positive and Gram-negative organisms, some viruses and some fungi. Chlorhexidine is most active at a neutral or slightly acid pH and its activity may be reduced by blood and other organic matter.

Cetrimide is a quaternary ammonium disinfectant with properties typical of cationic surfactants. Solutions of these surfactants have emulsifying and detergent properties and bactericidal activity against both Gram-positive and Gram-negative organisms but higher concentrations are necessary to kill the latter. The combined detergent and antibacterial properties of cetrimide make it useful in cleansing dirty or infected wounds.

Chlorhexidine and Cetrimide Irrigation Solution comes in two different strengths and contains the active ingredients chlorhexidine gluconate and cetrimide. The colouring agent Sunset Yellow is also present. These ingredients are dissolved in purified water.

Do not use it after the expiry date (EXP) printed on the label.

It may have no effect at all, or worse, an entirely unexpected effect if you take it after the expiry date.

Do not use Chlorhexidine and Cetrimide Irrigation Solution if the packaging is torn or shows signs of tampering.

Wounds may take longer to heal if cetrimide is used regularly. Therefore it is important to use this product as directed by the doctor.

You must tell your doctor if you have allergies to:

  • Chlorhexidine;
  • Cetrimide;
  • Any of the ingredients listed here;
  • Any other substances, such as foods, preservatives or dyes.

With the firm commitment to quality, we are engaged in manufacturing, supplying and exporting Chlorhexidine Base. This chemical is formulated using high quality ingredients that are procured from certified vendors of the market. Our offered chemical has a molecular formula C22H30Cl2N10 and molar mass 505.446 g/mol. This chemical is reckoned for pleasant smell, accurate composition and precise pH value. Chlorhexidine Base is widely used in mouthwash and contact lens solutions.

Other information:

Used in Base Antiseptic. Also known as Hexicare, it is a pleasant smelling all purpose disinfectant. The Hexicare is carefully formulated in compliance with international standards to ensure its effectiveness and its effects on skin or body.

CERTIFICATE OF ANALYSIS Sr. No. Test Specification 1 Description White powder. 2.

Identification

The Infrared absorption spectrum of the test sample should exhibit maxima only at the same wavelength as that of a standard spectrum of Chlorhexidine base working standard. 3 Melting Range Between 132º C and 136ºC 4 Residue on Ignition Not more than 0.1%.(w/w) 5 Loss on drying Not more than 0.50 % w/w 6 Assay by HPLC Not less than 98% w/w and more than 102% w/w 7 Assay by Titration Not less than 98% w/w and more than 102% w/w 8 p-Chloroaniline by HPLC Not more than 100 ppm 9 Colour Test at 480 nm Not more than 0.03 at 480 nm 10.

CHG 20% Test

Prepare a small batch of CHG 20% solution from CH base (statistically sampled from a lot) It should be a clear white solution meeting USP specs. % Related substance less than 1.0%. No undissolved substances in the CHG 20% solution 11 Contamination

There should not be any contamination in side or outside of the bags. No foreign particles, dust, metals etc. in product. 12 Microbial count Should be absent 13 Heavy metal Not more than 20 ppm

Chlorhexidine Base CAS No: 55-56-1 Formula: C22H30Cl2N10 Molecular Weight: 505.46 Class: Non Hazardous Application / Use: Antiseptic

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Author: Basic Pharma

Basic Pharma

Member since: Dec 14, 2018
Published articles: 6

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