Revolutionising Biological Component Detections With DNA And SPR Sensor Chips

Often scientists have been in doldrums regarding the manner in which their research work progresses in case of small molecules or particles. During the course of their experiments, there are often such hindrances, where minute microscopic structures are required to be revealed or detected. Their revelations will be helpful in progressing further into the experiments and the functions and structures of these molecules can be elicited. In recent years, there has been much advancement in the manner in which the protein structures of the biological components are studied. With the help of micro and macro array technologies, variety of biological structures is being revealed. This is being done through the help of sophisticated SPR sensor chips or surface Plasmon resonance technology.

• Microarray technology being preferred with highly advanced chip system of diagnosis

More number of microarrays is being designed to differentiate and separate specific substances from the fluid or gaseous mixtures. Among these films or plates, the DNA biochips have gathered attention. Due to the genome project, this kind of microarray gained more importance and the sensor chips of SPR were utilised to study the spectrum of DNA and RNA sequences. If these biochips are used in their full potential, then there will be extreme ease in studying various genetic sequences and the related diseases. In many biomedical research projects, there are DNA sequencing being done and genetic material is being reaffirmed.

• Forging usefulness of DNA based chips with resonance detection for lasting and resounding results

Although, DNA biochips have been in circulation for some time now, its association with biosensor technology has been recently brought to the fore. Combining the use of DNA microarray with SPR sensor chips is going to forge newer paths into the detailed study of genetic diseases and even reveal protein targets for their cure. Antigen antibody reactions have been studied in some diseases to bring out suitable treatment modalities. But, these techniques are required to be fine tuned in order to be applied on a large scale. Advanced SPR sensors are being designed, which will be stable along with lower reactivity with different kinds of biological fluid mixtures or their components. In the present day scenario, these pathways will lead to better diagnostic and therapeutic tests.

• Preparing designs of sensor chips for resonance with sharpness and ligands

Designing the SPR sensor chips is currently one of the biggest challenges for scientists, which would be stable as well as sensitive. The working of these sensors depends on the resonance of light from the chip surfaces. The chip will be then detected with the help of transducers and the observations can be shown by computer screens. If the sensors are good, then the chips can send even weak wavelengths for the complete reception. So, with detailed discussion of the DNA biochips and the designing of special tags, this medium can be highly expressive of the minutest of proteins. In the context of the scenario, research can be done using the chips with variety of tags and ligands, but the SPR technology can be quite superior form of receiving data dependably.

Kiran gracia is very much interested in Spr sensor chips and antibody coating fields and writes articles on them regularly.