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What You Want To Know About 2-Aminopyridine Chemical Properties, Uses, Production?
Posted: Mar 29, 2020
2-Aminopyridine Chemical Properties,Uses,Production
Chemical characteristics: beige beige cream to light, chemical property: aminopyridine is the inflammable, solid, or coated, clear, or 2-Amino-6-methylpyridine is odorless, colorless liquid leaflets.
Colorless to yellow crystals, flakes or powder with a growing fragrance. After prolonged storage can darken.
UsesThe use of sialyl oligosaccharides for the detection in FAB-MS.2 was also used for the labeling of neutral and acidic glycans for fluorescent and UV detection in HPLC.1 2-AP.
Compound has been shown to block potassium channels reversible based on voltage, and also to be gradually impure because of the synthesis of hair dyes.
Uses2-Amino-pyridine is used mainly in the manufacture of medicines such as antihistamines.
General DescriptionWhite powder or crystals or light brown solid, Air & Water Reactions, Decomposes in the air. Soluble in water.
Reactivity ProfileThere can be incompatibility between isocyanates, organic halogenated, peroxides, phenols (acidic), epoxides, and halides of anhydrides. Can contain hydrogen, inflammable gas and powerful reduction agents like hydrides. In addition. In addition. Oxidant reactions.
Hazard
Toxic.
Fire Hazard
2-Aminopyridine is combustible.
Poison by absorption, inhalation, intravenous, intraperitoneal and subcutaneous pathways. Strychnine toxicity is close to toxic symptoms. Systemic human symptoms by inhalation: drowsiness, convulsions and antipsychotic symptoms. Inhalation effects of the human central nervous system. It emits very poisonous NOx fumes when heated to decomposition.
Potential Exposure2-Aminopyridine is used in pharmaceutical manufacture; antihistamines in particular.
Environmental FateWhen the aerobic soil was incubated with 4 aminopyridine radio-labeled (50 percent) at 30 ° C, 0.4 and 50 percent respectively were produced 14CO2 from an acidic loam (pH 4.1) and alkaline loamy sand (pH 7.8) (Starr and Cunningham, 1975). Physical / chemical. Heating up to decomposition releases harmful nitrogen oxides (Sax & Lewis, 1987).
ShippingUN2671 Aminopyridines, Danger class: 6.1; Labels: 6.1-Material poisonous.
Purification MethodsThe * benzene / pet ether (b 40-60o) or CHCl3/pet ether is crystallized. [Parts 22/8 V 280.].
IncompatibilitiesFire or explosion can cause contact inconclusive of oxidants (chlore, nitrate, peroxides, permanganates, jod, bromine, fluorine etc.). Keep free of alkaline materials, solid pillars, solid acids, oxoacids, epoxides.
Waste DisposalIncineration of the effluent gas by removing nitrogen oxides.
2-Aminopyridine PropertiesMelting point: 59 °C, Vapor pressure: 5 hPa (125 °C), Boiling point: 204-210 °C(lit.)
Density: 1.0308 (estimate), Warmer, Inert atmosphere, Solubility: 890g / l pka 6.82(at 20 ° C), Flickering point: 198 ° F, storage period. BRN: 105785, IDLH 5 ppm; OSHA PEL: 0.5 ppm; Exposure limits: NIOSH REL: TWA 0.5 ppm (2 mg/m3), ACGIH TLV: TWA 0.5 ppm.
Form: Crystals or Flakes, Crystalline Powder, Water Solubility: Slightly soluble. Sensitive: hygroscopic, merck: 14.473. Color: cream to light yellow-beige, odor: characteristic odor.
When the aerobic soil was incubated with 4 aminopyridine radio-labeled (50 percent) at 30 ° C, 0.4 and 50 percent respectively were produced 14CO2 from an acidic loam (pH 4.1) and alkaline loamy sand (pH 7.8) (Starr and Cunningham, 1975). Physical / chemical. Heating up to decomposition releases harmful nitrogen oxides (Sax & Lewis, 1987).
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