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Oligonucleotide Manufacturing Market: Global, Annual Demand

Author: Srishti Khurana
by Srishti Khurana
Posted: Jun 26, 2020

At present, eight oligonucleotide-based drugs have been approved, while over 200 product candidates are being evaluated in various clinical trials across the globe. As the market for such therapeutic interventions continues to evolve, it is likely to induce a steadily growing demand for oligonucleotides. According to our estimates, the global annual demand for oligonucleotides is growing at an annualized rate of 13.2%, during the period 2020-2030.

As per the analysis, more than 65% of the current demand is likely to be driven by commercial oligonucleotide-based products. During the forecast period, the commercial demand for oligonucleotides is anticipated to grow at a CAGR of 14.7%. Further, the demand for antisense oligonucleotides is anticipated to be the highest in the coming years, growing at a CAGR of 9.8% in the given time period. In terms of therapeutic area, the manufacturing demand for oligonucleotides intended for the treatment of neuromuscular disorders is likely to be the highest, growing at a CAGR of 8.1%, in the given time period.

Further, as per our analysis, the clinical demand for oligonucleotides is likely to grow at a CAGR of 10%, during the period 2020-2030. As indicated earlier, in recent years, a large number of development programs have been initiated in order to evaluate oligonucleotide-based drug products for the treatment of different clinical conditions. As more such studies are expected to start in the coming years, the clinical manufacturing demand for oligonucleotides is expected to rise significantly.

It is worth highlighting that over 20% of the current clinical demand is anticipated to be driven by antisense oligonucleotides. However, the clinical demand for miRNAs and siRNAs is likely to grow at a CAGR of 15.9% and 10.4%, respectively. Further, the manufacturing demand for oligonucleotides intended for the treatment of oncological disorders is likely to be the highest in the coming years, growing at a CAGR of 5.2% during the given time period. Further, majority of the current demand for oligonucleotides is anticipated to be concentrated in North America and Europe. Further, the demand in Asia-Pacific and rest of the world is estimated to grow at a CAGR of 11.8% in the given time period.

In fact, in an interview with the founder and managing director of a small company, he stated that "Industry players are rapidly upgrading their businesses to meet the demand for therapeutic oligonucleotides. Further, majority of the GMP manufacturers are focused on increasing their capacity to produce better quality oligonucleotides for various emerging applications."

The "Oligonucleotide Synthesis, Modification and Purification Services Market: Focus on Research, Diagnostic and Therapeutic Applications, 2020-2030" report features a detailed study of the current scenario and future potential of the custom synthesis, modification and purification services market for oligonucleotides, which are intended for research, diagnostic, and therapeutic applications.

Key Questions Answered
  • Who are the leading manufacturers of oligonucleotides for use in research, diagnostic and therapeutic applications?
  • What are the preferred custom synthesis, modification and purification methods used for oligonucleotides?
  • What are the key challenges faced by oligonucleotide manufacturers?
  • What kind of partnership models are commonly adopted by industry stakeholders?
  • What are the recent expansion initiatives undertaken by service providers within this domain?
  • What is the annual clinical and commercial demand for oligonucleotides?
  • What is the current, installed manufacturing capacity for oligonucleotides?
  • What percentage of oligonucleotide manufacturing operations are outsourced to service providers?
  • What are the opportunities in emerging markets for oligonucleotide manufacturing?
  • How is the current and future market opportunity likely to be distributed across key market segments?
  • What are the anticipated future trends related to oligonucleotide manufacturing?

Complete report by Roots Analysis: Oligonucleotide Synthesis, Modification and Purification Services Market: Focus on Research, Diagnostic and Therapeutic Applications, 2020-2030

About the Author

Roots Analysis provides market research and consulting in the pharmaceutical industry. Focussed on providing an informed and impartial view on key issues facing the industry, our research is primarily driven by an in-depth analysis.

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Author: Srishti Khurana
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Srishti Khurana

Member since: Jun 03, 2020
Published articles: 53

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