Seroquel is an oral atypical antipsychotic drug. It is used for the treatment of mental disorders such as schizophrenia and bipolar disorder. The exact mechanism how this medicine works is unknown. It is believed that it works by inhibiting the communication between nerves located in the brain. Neurotransmitters are some chemicals which contribute to communication between nerve cells. This medicine works by blocking dopamine type 2 (D2) and serotonin type 2 (5-HT2) receptors.

Seroquel is used for the treatment of following health conditions

• Schizophrenia

• Bipolar disorder

• Episodes of mania or depression

Before taking this medicine

Seroquel is not used for treatment of psychotic conditions related to dementia. It can lead to pneumonia, sudden death, failure and stroke.

To ensure that this medicine is useful for you, you must inform your medicinal practitioner if you are suffering from any of the following problems:

• Liver or kidney disease

• Heart disease

• High or low blood pressure

• Cataracts

• Trouble swallowing

• Abnormal thyroid tests and protein levels

Dosage Information

Seroquel is prescribed as per the disease condition, age and sex of the patients.

Schizophrenia: The initial dose is 25 mg twice daily. It can be further increased to 300-400 mg/day in two or three doses.

Bipolar Disorder: The initial dose is 50 mg twice daily. It can be further increased to a daily dose of 400mg/day in two doses.

How to take this medicine?

• You must take this medicine with a full glass of water.

• You can take it with or without food.

• Try to swallow the capsule as whole without crushing, chewing or breaking it.

• It is seen that regular uptake of this medicine can enhance your blood sugar levels and lead to hyperglycemia. It is necessary to keep a check on your sugar levels by regularly checking your sugar levels in the blood.

• Never change the dosage of the medicine or stop taking without having any discussion with your doctor. It may worsen your disease condition.

Precautions and side-effects

• Blurred vision; swelling of face, lips, tongue, or throat; dry mouth; nausea, vomiting, and stomach pain are some of the side-effects that are associated with the administration of this medicine.

• Drugs such as lumefantrine, metoclopramide, mifepristone; medicines used for cancer treatment and dye used for an x-ray and CT scan can have drug interactions with this medicine. If you are taking any of the above mentioned medicine or related drug, it is essential to inform your medicinal practitioner.

Ezetimibe is a clinically proven drug which is used for the treatment of schizophrenia and bipolar disorder.

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