Ezetimibe is a generic drug which is used to lower the plasma cholesterol levels. It mainly works by localizing at the brush border of the small intestine where it inhibits the absorption of cholesterol from the intestine. NPC1L1 protein is responsible for cholesterol absorption in the gastrointestinal tract. Ezetimibe binds to critical mediator of cholesterol absorption. Moreover, there is an increase in the LDL-receptors on the surface of the cells, resulting in increased uptake of LDL-cholesterol into cells. Therefore, reduction is level of bad cholesterol in plasma is noticed within few days after regular administration of this medicine.

Ezetimibe is used for treatment of following health complications

• Hypercholesterolemia

• Homozygous sitosterolaemia

Before taking Ezetimibe

It is seen that this medicine is not suitable for some people with below mentioned health conditions. If you having any of the below mentioned health condition, it is highly advised to consult with your pharmacist or doctor before start using this drug.

• Pregnancy

• Liver Disease

• Allergic reaction to some drugs

Dosage Information

The general prescribed dosage of this medicine is 10mg once daily.

How to take this medicine?

• Before start taking regular dose of this medicine, you must read the prescription label available with it carefully.

• You can take it with or without food.

• Never make any alterations in the dosage of this medicine without making any prior discussion with your doctor.

Missed Dose and Overdose

To enhance the effect of the medicine, it is necessary to take it on same time daily. Never miss any dose. In case, you have missed a dose, then do not worry. You can take it whenever you remember. However, do not take a double dose to compensate for the missed dose. Also, if the time of next dose is approaching then continue with your regular dose by skipping the missed dose.

The overdose of this medicine does not produce any life-threatening symptoms. In case, you have taken this medicine in large quantity, it is recommended to take medical attention immediately.

Precautions and Warnings

• It is essential to take low-fat diet along with the administration of this medicine.

• If you are taking this medicine for a longer time period, it is essential to get your liver function tested in a regular manner.

• In few cases, it is seen that people taking this medicine can face some problem such as pain, tenderness or weakness in the muscles. Such people must take a laboratory test to check the levels of creatinine phosphokinase (CPK) in the blood.

Ezetimibe is a generic medicine which is used to decrease levels of LDL-cholesterol in the blood plasma.

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