Cell fate regulation by gelsolin in human gynecologic cancers

Ovarian cancer is the most deadly cancer in female gynecological diseases, studies have shown that a woman's chance of about 50% in the period of their life will suffer from the disease, researchers in Ottawa and Taiwan. the article about why the ovary cancer is usually on the chemical therapy with this view resistance provides new insights, and to improve the diagnosis and treatment of the method provides a possibility.

According to the "Canadian" Journal of ovarian cancer related data to estimate, in 2014 about 2700 Canadian women diagnosed with ovarian cancer, about 1750 women were killed. The disease is usually can be diagnosed in the late stage, while the ovarian cancer chemotherapy has produced resistance to.

These findings are better able to help clinicians to diagnose ovarian cancer patients, the key is to understand the role of calcium binding actin protein. The formation of growth in the protein level and ovarian cancer related, which is likely to cause ovarian cancer resistant to chemical therapy.

The researchers showed the process of calcium binding microfilament protein for the protection of how cancer cells at the molecular level. The discovery is very important, because it will help clinicians according to the amount of actin binding proteins calcium to determine the most effective treatment scheme. But the work is needed to determine the very precise microfilament protein amount of calcium binding, because the amount of determination can be explicitly formulate specific solutions for cancer chemotherapy resistance held etc..

In addition, the ovarian cancer cell of a same protein are resistant to chemical therapy can overcome obstacles on this treatment. By cutting off the calcium binding actinprotein to divided into special fragment, and the fragment will be embedded into the chemotherapy resistance in cancer cells, the team found that these cells are very sensitive to the chemotherapy drug cisplatin with tumor killing effect becomes.

Recent studies show that, in Germany every year there are about 11.2/100 000 of women will get cervical cancer. Persistent infection with high-risk human papillomavirus(HPV) is a poor and cervical neoplasia cervical development a necessary prerequisite.

Human papillomavirus vaccination is a controversial and the topic of discussion,because in 2007. It was incorporated into the German Standing Committee recommended vaccination (STIKO). The researchers conducted a systematic review showed protection against type 16 and type 18 HPV vaccine for more than 5 years.

The German market authorization are vaccines for type 16 and type 18 Hpv virus, because these two viruses are the most common type of risk in Germany. Before the two type HPV virus infection to human vaccination can provide protection, so do the prevention of foundation of HPV infection of cervical cancer.

Sexual contact is the main way to the spread of the HPV virus, in 12 to 17 years old girls and young women without sexual contact in vaccination is the most effective way to prevent HPV. The researchers investigated the HPV vaccine for girls and women to the effect of vaccination through short-term and long-term follow-up. However, the number of small research and participants can show the vaccine long-term protection of the quality of evidence is lower than the short-term protection of the quality of evidence.

In order to improve the quality of vaccine of long-term protection of evidence, the researchers decided to continue the randomized controlled trial was conducted in order to furtherdetermine the duration of protectionof HPV vaccine, and observational study to evaluate the efficacy of the vaccine.

Numerologist Warda is hooked on OG-L002 fishing, collecting. And lastly her encouragement comes from socializing along with her companions.