How Does Stem Cell Therapy Help Parkinson’s Patients

Parkinson's Disease is a neurodegenerative disorder that affects nearly 10,000,000 people worldwide. It begins with harmless symptoms but can progress to become restrictive and cause anxiety or depression.

While traditional Parkinson's treatments focus on treating symptoms, stem-cell therapy has been shown to improve everyday functionality and life quality.

This blog will first briefly describe the symptoms of Parkinson’s and its typical characteristic before moving on to the stem cell treatment that can be used in India for Parkinson’s.

Understanding Parkinson's

Parkinson’s disease is a degenerative, chronic brain disorder that affects muscle control, movement and balance. It leads to the degeneration and death of cells within the substantia nubra (basal ganglia). It prevents the brain from producing dopamine, the happy hormone. The disease causes the brain neurons to completely degrade. The symptoms include severe motor impairment, tremors or stiffness, slow or delayed movements, dysphagia (dysphagia is a condition where the mouth moves slowly), fatigue, sleep problems, and difficulty speaking.

Parkinson's symptoms

Parkinson's is characterized by a number of symptoms.

Tremor

Drooling

Dysphagia

Dizzy spells

Slurred speech

Stooped posture

Dragging your feet

Depression and anxiety

Spasticity of the limbs

Hypomimia is a masked or hidden face

Shaky hands, lips, fingers

Instability and poor coordination

Micrographia (or small handwriting)

Incontinence and loss of bladder control

Hypophonia (or unusually soft voice)

Numbness and weakness of the limbs

Slowing movement (bradykinesia).

The ability to control movements such as blinking, smiling or blinking

Standing up from a prolonged sitting position and vice-versa.

Muscle control loss on first one side then the opposite

Dyskinesia - uncontrollable, involuntary movements like jerks, twitches and twisting movements

Before diving into the intricacies stem cell therapy, let's examine two cases handled by Team Plexus. The team is led by Dr Na’eem Sadiq - India's stem cell expert.

From depression towards confidence

In 2014, a 58 years old Bangalore-based businessman named Mr J started to experience tremors. At first, Mr. J didn't pay much attention to them and dismissed the spells of trembling as nothing more than tremors. When Mr J started experiencing more severe symptoms such as muscle discomfort, stiffness and uncontrollable movements, he consulted with several doctors. Sadly, all of them gave the same diagnosis - Parkinson's. The condition gradually began to affect Mr J in every way, and often left him unable to do his normal daily tasks. M J also began to suffer from facial tremors which made it harder for him to clearly speak. In no time, the daily battle against Parkinson's was eating away at Mr J's motivation for social interaction, pushing him even closer to depression. He tried clinic after clinic looking for a permanent remedy to alleviate his condition but was constantly disappointed. Plexus’ multidisciplinary team was introduced to Mr J by Plexus in April of 2015. We investigated his condition in detail and created a tailored treatment program. In just two months, the symptoms of Mr J became less intense. His speech also became clearer. And he regained his confidence to be able to live independently. Plexus's stem cell therapy put Mr J on a fast-track to recovery and helped him believe in himself.

A step towards good health

Mr A is a 35 year old Londoner who was shocked in 2010 when doctors told him the slight tremors and slowing down of his walking were signs of Parkinson’s. Mr A was back in Delhi the following year where doctors advised him to do some physical exercises. However, due to his extreme pain, numbness, poor posture, and other symptoms, this was not something he could really do. Mr A was plagued with Parkinson symptoms and side effects from steroids for seven long, painful years following his diagnosis. In this state, Mr A, who had given up on hope and was at the end of his wits, began a gradual descent into depression. His wife's optimism as well her insistence to take him to different Ayurveda specialists, homeopathic practitioners and allopathic doctors kept his spirits high. Plexus Neuro Stem cell Research Centre came to Mrs A's attention one day when she was online looking for treatments. The couple immediately contacted Dr Na'eem Sadiq. She convinced them to travel to Bangalore in 2018, for stem-cell therapy. During his two-month intensive session, Mr A went through a holistic treatment program, which included stem cells therapy, physiotherapy and occupational therapy. In addition to the prescribed nutritional supplements, Mr A was given a diet that matched his needs. Mr A. was left with a lasting impression by the Plexus Centre's international healthcare standards. He also appreciated the attention and care provided by the Plexus Team and Dr Sadiq. After many years of avoiding his hobbies, he participated in the singing and art competitions that were organized by the centre to celebrate his recovery. With the assurance of good health at the end of the treatment period, Mr A left his centre a transformed man.

Stem Cell Therapy to Treat Parkinson's

Stem Cells are undifferentiated, unaffected cells that have an incredible capacity to transform into many different types of cells. This unique characteristic makes them ideal for regenerative medicine.

Healthy stem cell are introduced into brain to replace damaged neurons or restore normal functioning. The procedure offers great promise in slowing down or stopping the progression Parkinson's. Plexus's customized regenerative Parkinson's program includes mesenchymal-stem cells (MSCs). MSCs' regenerative properties, anti-inflammatory effects, and immunomodulatory abilities make them an attractive candidate to combat the pathology of Parkinson’s.

Look at MSCs' characteristics and see how they contribute to improving the quality of life of Parkinson's sufferers:

Regenerative Ability

Neuronal Differentiation

MSCs can be differentiated into various cell types. This includes neurons. Once they're introduced into your brain, MSCs can replace damaged or missing dopamine neurons.

Neurotrophic factors production

MSCs produce neurotrophic agents that encourage the growth of neurons and their survival. This neuroprotective effects is essential to prevent further degeneration of the dopamine-producing neurons.

Effects on Immunomodulation and Inflammation

Reducing Neuroinflammation

Neuronal damage occurs in Parkinson's due to inflammation. MSCs are anti-inflammatory and help to modulate inflammation, creating a better environment for neuronal health.

Immunomodulation

MSCs, with their ability to modulate immune systems, suppress harmful responses and promote anti-inflammatory environments, can significantly reduce autoimmune components often associated Parkinson's.

Enhancing Neuroplasticity

Promoting the Synaptic Connectivity

MSCs may enhance synaptic communication between neurons. This is essential for improving motor, cognitive and other functions of the Parkinson's brain.

Reduce Motor Symptoms

Improve Motor Function

MSCs, by differentiating or promoting the life of existing neurons and producing dopamine, may help restore dopamine and alleviate motor symptoms.

Parkinson’s Stem cell treatment is a paradigm-shifting approach to treating Parkinson’s. As stem cell therapies have proven to be effective in relieving pain and avoiding side effects from drugs and surgery, doctors are increasingly recommending them as a treatment for chronic illness. Plexus' mission is to make this miracle available to people in the most desperate need.

Team Plexus has more information on stem cell therapy.

WhatsApp +91 98448 42087

Call +91 781 64668 in Hyderabad

A highly regarded neurologist and stem cell specialist, Dr Na’eem Sadiq studied neurology and clinical neurophysiology in London before working with some of England’s and the Middle East’s most prestigious medical institutions. He completed his MBBS