Lab-Scale Rapid Mixer Granulator: Perfect for Small-Scale Granulation Trials

Welcome to VJ Instruments, your trusted partner in innovative solutions. We are thrilled to present our groundbreaking Rapid Mixer Granulator, meticulously crafted to handle smaller trial batches with precision in the world of granulation. Explore how this cutting-edge machine can elevate your processes, providing unparalleled flexibility and cost benefits.

Rapid Mixer Granulator is designed for mixing the ingredients and wet granulation for tablet and capsule manufacturing process. This efficient machine achieves it by consistent mixing, uniformity of granule size and reducing process time. Moreover, rapid mixer granule is complaint to cGMP norms and maintains high standards of hygiene. The Lab Rapid Mixer Granulator is used in laboratories for research and development due to which it is also known as R&D Rapid Mixer Granulator. It is also known by the names Mini Rapid Mixer Granulator, Small Rapid Mixer Granulator and Compact Rapid Mixer Granulator due to its small and compact size.

The Rapid Mixer Granulators are characterized by their compact construction and user-friendly attributes make it very useful to perform dry mixing and wet granulating. Since it is widely used in pharmaceutical manufacturing processes, it assures a great reduction in the processing time. It serves as an instrument for research and development purposes owing to its homogenous mixing capabilities and controlled granule size and is most popularly called the R&D Rapid Mixer Granulator. The Mini Rapid Mixer Granulator uses the shear mixing principle for mixing and agitation to ensure contamination-free operation. This becomes important because of its extensive application in pharmaceutical industries, the small rapid mixer needs to have efficient processing and large-scale performance.

MIXING BOWL:

The mixing bowl is circular in shape and it has large diameter and flat base. The top part of the bowl is designed in conical shape so that it is easy to mix cohesive powders. It is very sturdy as it is made of SS 316/ 316L. The drive shaft is surrounded by a tube with large diameter, where it enters the base part of the bowl.

It has the main drive, shaft seal on the top of the tube so that it can be above the normal powder level. The shaft seal comes with an automatic air purge. On flushing the seal housing and drive shaft with cleaning water, discharge port drains it away from the machine. As per the design, the multi-bladed impeller is fixed close to the mixing bowl base and the chopper is fitted on the mixing bowl wall. To softly disturb the binder solution and create the vortex of the material being mixed, the impeller and the chopper comes with dual speed options.

GRANULATOR:

A high-speed lab rapid mixer granulator efficiently assists the blending of powder and breaks the product to granule of desired size.

The granulator rotation is available in two speeds - 1500 or 3000 RPM. The granulator head is very sturdy as it is made of polished stainless steel and it can be easily removed for cleaning.

The Granular Shaft includes Air Purged Seal where it connects to the bowl.

The motor comes with removable stainless steel covers as per the cGMP norms.

Rapid Mixer Granulator (RMG):

A Workhorse for Pharmaceutical Manufacturing The Rapid Mixer Granulator (RMG) is a crucial piece of equipment in the pharmaceutical industry. It's a multi-talented machine that excels at: Mixing Ingredients: The RMG efficiently combines various powdered ingredients to ensure a uniform mixture. Wet Granulation: This process transforms fine powders into larger granules, making them easier to handle and compress into tablets or capsules.

How Does the RMG Work its Magic?

The RMG's secret lies in its design: Bottom Entry Agitator: This slowly stirs the ingredients in the bowl, promoting even distribution. Side-Mounted Chopper: This high-speed blade chops and mixes the wet mass, forming uniform granules. The processing time depends on the number and size of the ingredients being mixed. Keeping the RMG in Top Shape: The Importance of Purging Air Just like any other equipment, the RMG needs proper care. Purging air is a technique that uses clean air to flush the machine. This helps remove residue and maintain optimal performance.

Granulation:

The Art of Making Powders Behave Granulation is a common process in pharmaceutical manufacturing. It takes fine, loose powders and transforms them into larger, more manageable granules. These granules are ideal for further processing into tablets or capsules. Why is Granulation Necessary? There are several advantages to granulation:

Improved Flowability: Granules flow more smoothly than fine powders, making them easier to handle during processing.

Enhanced Compaction: Granules compress better than powders, leading to stronger and more uniform tablets. Reaching the

Granulation Sweet Spot: The End Point The granulation end point is the desired size and distribution of the granules. Once this point is reached, the granules are ready for further processing. Throughout the process, measuring factors like viscosity and density helps estimate the granule size and distribution.

Wet Granulation: A Closer Look Wet granulation involves adding a liquid solution to dry powders. This liquid helps the powder particles clump together, forming granules. The complexity of this process depends on the specific powder characteristics and the equipment used.

WHAT IS DRY GRANULATION PROCESS?

The dry granulation process is used for forming granules without any liquid solution. It is most suitable for the materials that are moisture-sensitive, heat-sensitive or do not compress well. Dry Powder granulator effectively executes this process with compacting and size reduction of the mix to create a free-flowing blend of uniform size. The primary powder particles are aggregated at high pressure with the help of high shear mixer granulator.

Fluid Bed Processors in Pharmaceutical Granulation Fluid bed processors are a cornerstone in the pharmaceutical industry, particularly in the granulation process.