Pazopanib - Votrient: Targeted Therapy for Treating Soft Tissue Sarcoma

Soft-tissue sarcoma is a rare kind of cancer which forms in the tissues that surround body structures. Such tissues include the blood vessels, nerves, tendons, muscle, fat and lining of the joints.

Currently, around 50 types of soft-tissue sarcoma have been identified. Certain kinds of soft-tissue sarcoma are likely to be diagnosed in children while others are more likely to be diagnosed in adults.

Soft-Tissue Sarcoma is difficult to diagnose because it can be easily be confused with other forms of growths.

This cancer can occur in anywhere in the body but can commonly form in abdomen, legs and arms.

The most common form of treatment for such a cancer type is surgical removal of the tumour. Depending on factors such as location, type, growth rate or size of the tumour, chemotherapy or radiation therapy may also be performed.

Standard treatment options for standard soft-tissue sarcoma involve a single agent or combination systemic chemotherapy. However, the success of such treatment varies depending on factors like tumour heterogeneity and cellular mechanisms of chemoresistance.

Targeted therapy treatment for soft-tissue sarcoma

Targeted therapy involves the use of medications to identify and affect the cancer cells while also keeping the normal cell unharmed, by attacking the part of the cancer cells that distinguishes them from normal cells.

As doctors continue to observe the biology of sarcoma cells, targeted therapy using medications such as Pazopanib / Votrient is becoming a viable treatment for treating soft-tissue sarcoma.

Pazopanib / Votrient cost information

Pazopanib mechanism of action

Pazopanib / Votrient works by inhibiting tyrosine inhibitor (a type of cell enzyme) that enable tumour cell growth.

It is generally used to treat advanced soft-tissue sarcoma that has not responded well to chemotherapy. It helps in reducing the growth rate of the tumour and lower side effects experienced by the patient.

It is uncertain if this medication can increase the life span of the patients.

Pazopanib / Votrient side effects

Some common Pazopanib side effects include:

• Nausea and/or headache
• Problems in the liver
• Low count of blood cells
• Diarrhea
• Fatigue
• High blood pressure
• Change in hair colour

Some side effects such as bleeding and clotting problems are more severe but are also rare.

Another severe but rare side effect of taking Pazopanib tablets is problems with heart rhythm or even a heart attack.

For patients taking Pazopanib / Votrient tablets, doctors do blood tests to check for any liver problems and monitor the heart with EKGs.

Pazopanib / Votrient comes in the following dosages:

• Generic Pazopanib / Brand Votrient 200 mg tablet
• Generic Pazopanib / Brand Votrient 400 mg tablet

Pazopanib cost information

The information provided on the page is meant for the purpose of being helpful and educational. It should not be considered as medical advice.

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