Zhang Qing

A new target which may be used in the therapy of neuroblastoma was identified by Scientists from University of Liverpool. This study could accelerate the development of new drugs against...

Scientists from University of Luxembourg have identified a new effective biomarker which could be used to detect colorectal cancer. The study was published in British Journal of Cancer. Despite...

Patients aged at least 40 years with a predefined IPF diagnosis of less than 5 years prior to the study screening were included in the study. Eligible patients had a FVC?50% and a DLCOpred 30-79% and...

Nicotinamide N-methyltransferase (Nnmt) methylates nicotinamide using SAM as a methyl donor and generates S-adenosylhomocysteine (SAH). SAM has two major functions: on hand, providing propylamine...

Telomerase plays a key role in bypassing cellular senescence and maintaining telomere homeostasis, essential properties required for the sustenance and progression of cancer. However, recent...

A recently published research reports that investigators have developed a novel strategy for reducing the often serious side effects of an important class of modern anticancer drugs -- tyrosine kinase...

We have exhibited below for your first-time that remedy together with the container-deacetylase inhibitor panobinostat quickly lowers the activity of DNMT1 and DNMT3a in two liver cancer cell lines in...

Crizotinib is an anti-cancer drug acting as an ALK (anaplastic lymphoma kinase) and ROS1 (c-ros oncogene 1) inhibitor, approved for treatment of some non-small cell lung carcinoma (NSCLC) Crizotinib...

I have been reading a lot of reports and articles about pharmaceutical companies cut cost and the whole industry are probably declining. Family-owned BoehringerIngelheim is no exception. The drugmaker...

The combination of letrozole with either the CDK4/6 inhibitor LEE011 or the PI3 kinase Inhibitor BYL719 demonstrated clinical activity for women with ER-positive, HER2-negative breast cancer...

PTEN is a lipid phosphatase that converts phosphatidylinositol-3, 4, 5-trisphosphate (PtdInsP3) into phosphatidylinositol-4, 5-bisphosphate (PtdInsP2) and antagonizes phosphoinositide 3-kinase...

The popular non-steroidal anti-inflammatory drugs, such as aspirin, naproxen and ibuprofen, play their roles by inhibiting cyclooxygenase enzyme. Cyclooxygenase can catalyze the generation of...

In July 9, "New England Journal of Medicine" (NEJM) published the results of a drug research: Researchers discovered a new drug, called dupilumab, can be used to treat the most common skin disease...

It's good news for a substantial number of patients that scientists have developed blood and saliva tests that help accurately predict returns of HPV-linked oral cancers. As known, the tests screen...

An asymmetric cell division produces two daughter cells with different cellular fates. This process is very important for the formation and development of cancer and has significant therapeutic...