Zhang Qing

Comparative studies showed that several proteins already found to be packaged into HIV-1 particles through specific interactions with viral proteins or nucleic acids are also detected in HIV-2 and in...

Epigenetic alterations (global DNA hypomethylation, regional DNA hypermethylation and aberrant histone modification) can influence the expression of oncogenes and lead to development and progression...

Our information reinforce the notion of the function of hypomethylation in early lymphomagenesis and shed light on underlying mechanisms. Materials and approaches Ethics statement Human samples made...

"Diabetes is unfortunately rising in prevalence around the world, driving up system costs and, most importantly, adversely impacting the lives of millions of people. Like Sanofi, we believe there is...

Rapamycin, the inhibitor of the mammalian target of rapamycin, has been shown to induce autophagy and inhibit proliferation of malignant glioma cells. Autophagy is negatively regulated by the...

With the applications of multi-omics approaches to examine the epigenome, the?eld of epigenetics is poised to change. We focus on the integration of omics approaches as applied to DNA modi?cation for...

Long-term, localized delivery of small molecules from a biodegradable thin film is challenging owing to their low molecular weight and poor charge density. While MIT researchers recently developed a...

Calcineurin (CN) senses Ca2+ concentrations and transduces that information into cellular responses. Signaling through CN plays critical roles in processes ranging from stress response survival in...

For the past two decades, researchers have been exploring B-cell specific antigens in hopes of developing a new anticancer target that would mirror the success of the CD20-targeting rituximab...

CYC202, a pharmacological inhibitor of CDK2, successfully inhibited reproduction of HAART proof HIV and wildtype -1 mutants in TO- PBMCs and monocytes, cells revealing that CDK2 action is required...

Micro RNA, a class of non-coding single-stranded length RNA containing about 22 nucleotides, is closely related with significant disease such as tumors, heart disease and neurological diseases, and...

Recent research, published in the journal Cancer Cell, reports that scientists have identified and characterized mutated versions of the genes that encoding BCR-ABL, the unregulated enzyme driving the...

Recently, researchers have developed a new approach to block the KRAS oncogene, one of the most frequently mutated genes in human cancer. The approach relies upon siRNA to attack KRAS, which is...

Last weekend, we visited a nursing home for the elderly. Most of them are suffering from Alzheimer’s disease (AD), which make them forget a lot of things, even their relatives and friends. As is...

Cholangiocarcinoma is a malignant tumor occurring at left and right hepatic duct, primary hepatic duct, and common bile duct of pancreas. Progressive obstructive jaundice is the main clinical symptoms...