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In living systems, nearly all biological functions arise from complex interactions among proteins. Individual proteins rarely act independently; instead, they associate with specific partners to...

Protein function is determined not only by amino acid sequence but also by a wide range of precisely regulated post-translational modifications. Acylation, an important category of these...

How can researchers capture ultra-low-abundance peptide signals in complex biological matrices and identify those with true biological relevance as peptide biomarkers? Peptides are structurally...

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In efforts to understand how proteins function and where these functions are executed inside the cell, subcellular spatial localization has become increasingly important. Changes in protein...

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