Treatment of Alzheimer’s Disease: A New Horizon

Alzheimer’s disease involves a gradual deterioration of memory, a decline in cognitive abilities, and challenges in performing everyday tasks. Dementia is primarily driven by this leading factor. Upon closer examination, statistics show that 80% of dementia cases are attributed to Alzheimer’s (Source: Alzheimer’s Association). Despite the rapid advancements and growing insights into the human brain, the root causes of diseases remain elusive. Treatment for Alzheimer’s disease is challenging due to the limited understanding of its underlying causes.

Like there are tons of new studies popping up that showcase some super cool meds and next-level therapies, like stem cell treatment, which is giving us some serious hope for handling the disease better. In this blog, we are going to discuss how stem cell therapy for Alzheimer’s is providing hope to the patients.

Traditional Approaches to Alzheimer’s Treatment

So when it comes to the Treatment of Alzheimer’s Disease, we are currently focused on managing and allevating the symptoms. But what is truly the need of the hour is an approach that addresses the core of Alzheimer’s. We know there is one sure reason that contributes to the progression of disease. Researchers have named them amyloid plaques. Because the situation is pretty serious and cases keep going up, researchers have managed to come up with a few drugs. So, like, the drugs that we are talking about are donepezil, rivastigmine, and memantine. The main goal of these meds is to slow down how the symptoms get worse. Just to be real, these meds don’t actually stop the disease from getting worse; they just help to slow it down a bit.

To imagine this, you can think of it as: let’s say normally it takes 1 year for symptoms to worsen, then with this drug the worsening will

happen by, say, 1.5 years. This hypothetical example shows how the drugs do reduce the degeneration rate, but it does not stop it. What’s more, these drugs influence the chemical centers that influence memory and cognitive abilities. This provides a modest yet significant form of relief.

So, like, the FDA just gave the green light to some interesting medicines like lecanemab (Leqembi). This drug is unique in its ability to target those pesky amyloid plaques in the brain. Now to be able to target them is a huge deal when it comes to Alzheimer’s disease. They are not our traditional medications, but they are rather like immunotherapies. They help our brain to get rid of the nasty amyloid buildup in the brain. Use of this drug have shown some promise in clinical trials, but they definitely come with risks. We would say these risks are skewed towards the high danger signals. There’s a chance of cerebral edema or hemorrhage, both of which are kind of serious. They can also lead to life threatening conditions.

A New Frontier: Stem Cell Therapy for Alzheimer’s

So, like, even though the meds we have now help with symptoms, there are some fresh ideas being looked at to really tackle the problem more effectively. One cool approach is "Stem Cell Therapy for Alzheimer’s." This therapy is all about bringing back those damaged brain cells, tackling the real issue behind Alzheimer’s instead of just dealing with the symptoms.

So, like, in India, clinics are totally getting into stem cell treatment for Alzheimer’s. They’re using stem cells more and more to tackle neurological issues. Stem cells can totally turn into different types of cells, like neurons, which are super important for how our brains work. Scientists are looking to transplant these cells into the brain to replace the damaged ones from Alzheimer’s disease, which could totally stop or even turn back the decline in cognitive function.

Why Stem Cell Therapy?

Stem cell therapy, or SCT in short, is being hailed as a revolutionary treatment. It is all because of the ability of the stem cells to repair and regenerate damaged tissue. These cells can be attenuated or primed to find the damaged tissue and then repair it. Several preclinical trials have shown that stem cells can be used to better the conditions of animal models when stem cells are used. If you wish to read this research, we are sharing some studies with you. Neishaboori et al. 2022 DOI: 10.1002/prp2.977, Regmi S et al. 2022 DOI: 10.3389/fnmol.2022.1011225, and Fan et al. 2014 DOI: 10.1002/med.21309. These review articles raise valid questions and give ideas of how stem cells are actually transforming the treatment of Alzheimer’s disease.

There are a bunch of different stem cell sources that people are checking out for treatment options. Researchers are using cells from bone marrow, fat tissue, and umbilical cords. So, like, there’s a chance we could use induced pluripotent stem cells in clinical trials, which is pretty cool. But there are a bunch of rules and ethical vibes we need to think about with these. So, like, the early stage clinical trials are looking pretty promising, right? Stem cells are showing some solid potential for boosting memory, cognitive skills, and just everyday stuff.

Here’s how stem cell therapy for Alzheimer’s offers a promising avenue for future treatment:

• Regeneration of Brain Cells: Stem cells can differentiate into neurons. This can potentially replace the brain cells damaged by Alzheimer’s disease.

• Reduction of Inflammation: Inflammation plays a significant role in the progression of Alzheimer’s. Stem cells can modulate immune responses and reduce inflammation. This enables the brain to prevent further damage.

• Potential to Slow Down Disease Progression: Stem cell therapy has the potential to target the underlying cause, slowing or halting disease progression.

Challenges and Future Outlook

Even though it sounds super promising, stem cell therapy is still just in the experimental phase for Alzheimer’s disease. There are some major roadblocks we need to tackle before this therapy can really become the standard treatment. The researchers and doctors have to go through a long list of regulations and ethical concerns. If they overcome this, the tricky nature of the disease means doctors cannot predict what will happen.

That said, there are several places, like India, where the service providers are able to overcome and comply with all the regulatory and ethical concerns. This is the reason why Stem Cell Treatment for Alzheimer’s in India is turning into a super appealing choice for patients from around the world. Clinics are totally serving up next-level treatments for way less than what you would pay in Western countries, so it’s a solid choice for a lot of people.

Conclusion

Even though we are still trying to find a cure for Alzheimer’s, the progress in the medical realm is giving us hope. This hope comes in the form of drug therapy and innovative treatments like stem cell therapy. With new drugs that tackle those amyloid plaques and combining them with SCT that can regenerate brain cells. We could be moving towards a future where Alzheimer’s isn’t just a permanent struggle anymore.

If you or someone you know is facing Alzheimer’s, hitting up your neurologist ASAP is a solid move. With all the cool research going on

, we could be super close to discovering a treatment for Alzheimer’s disease. That’s pretty lit, right? If you’re curious about whether stem cell therapy for Alzheimer’s could be an option for you, hit us up at +919654321400.

We are pioneers in stem cell manufacturing, empowering hope and healing for thousands worldwide seeking regenerative medicine.