Caroline Green
Member since: Jul 26, 2015
Published articles: 38
Among the many cancer-related genes, TP53 is one of the best studied, known for its tumor suppressor role. It acts as a "sentinel" that monitors abnormal cellular activity, senses cellular stress or...
Portuguese researchers analyzed the genome of monkeypox virus (MAPX) outbreaks in multiple countries and found that these samples clustered together, indicating that they had a single source...
Epigenetics was proposed in the 1950s by Conrad Waddington, a British developmental biologist, to describe the interaction between genes and the environment during development, thereby regulating and...
A new study clarifies how BRD4 (a protein that scientists have studied for many years) directs the spatial organization of DNA in the cell nucleus (a key function of stem cells to differentiate into...
Cell growth and division require the production of new proteins. This also applies to cancer cells. In a new study published in the journal Science Progress, researchers at the Carolinska Institute...
Epigenetic modifications play a crucial role in various biological processes and diseases, and DNA methylation is an important mechanism of epigenetic inheritance. DNA methyltransferases (DNMT1...
A team led by Professor X. David Li, Department of Chemistry, University of Hong Kong, has developed a new chemical tool to elucidate the network of intracellular protein interactions. This tool not...
Genetics (i.e., mutations) are considered to be the main factor predisposing to the etiology of rheumatoid arthritis (RA), but they account for only a few changes in RA disease risk, and in contrast...
Researchers at Baylor College of Medicine and its collaborating institutions have engineered immune cells to control two major life-threatening complications, graft-versus-host disease (GvHD) and...
The anti-apoptotic myeloid cell leukemia 1 (MCL1) protein belongs to the BCL2 family that supports survival and is frequently amplified or upregulated in human cancers. MCL1 is highly unstable and its...
Recently, research led by Dr. Francesca Marassi, a professor at Sanford Burnham Prebith, is helping to reveal the molecular secrets of macular degeneration, which causes almost 90% of age-related...
In recent years, immune-based cancer treatment methods have given doctors and patients a lot of hope. Drugs called immune checkpoint inhibitors have provided life-saving benefits to more and more...
The interesting SARS-CoV-2 omicron mutant strain evades immunity mediated by antibodies from vaccination or infection with early mutants due to the accumulation of a large number of spike mutations...
In a recent study published in The Journal of Neuroscience, scientists from Mount Sinai Hospital have discovered that a specific protein called RGS4 (Regulator of G protein signaling 4) may play an...
Chimeric antigen receptor T cell therapy (referred to as"CAR-T") is increasingly being applied to the treatment of cancer patients. CAR-T cell therapy has shown encouraging results in patients with...