Tumors with brain metastases often have a poor survival prognosis, including patients with a variety of high-risk pediatric tumors, such as high-risk neuroblastoma. In addition to the currently used...

Cancer vaccines have shown clinical promise in driving tumor-reactive cell activation, proliferation, and effector functions. Cancer vaccine therapy, on the other hand, has not been successful in...

There is a group of "old but immortal" cells in our body, namely senescence cells that have a unique phenotype, i.e. they are not productive but also refuse to "give way", not only preventing tissue...

In a biological context, reactive oxygen species (ROS) are natural byproducts of normal oxygen metabolism and play an important role in cell signaling and homeostasis. Excess reactive oxygen species...

A major study led by Professor Jennifer Doudna, a pioneer in the field of gene editing, has recently been published online in the leading academic journal Cell, and has attracted the attention of many...

When we go to the hospital or have a medical checkup, we basically have a blood test to get blood biochemical indicators like blood glucose, blood lipids, liver, and kidney function. These indicators...

In preclinical models of SCLC, CD47 blockade was found to be effective in enhancing the local antitumor effects of radiotherapy. "Radiotherapy in combination with CD47 blockade elicits a...

Acute myeloid leukemia (AML) is a clonal malignant proliferative disease of the hematopoietic system's myeloid primitive cells that is highly heterogeneous, usually incurable with chemotherapy, has a...

The current diagnostic criteria for SSD place a greater emphasis on patient behavior assessment and frequently involve patient self-assessment, which is very subjective and not helpful for early...

There is mounting evidence that the enzyme MAPK4 is involved in cancer growth and resistance to specific therapies. Researchers from Baylor College of Medicine and other institutions discovered that...

Yu Jun's team from The Chinese University of Hong Kong published a paper in Gut (IF=32) titled "Cigarette smoke promotes colorectal cancer through modulation of gut microbiota and related metabolites...

Many serious diseases are caused by viruses, such as the new coronavirus that caused a global epidemic, the terrifying Ebola virus, and even the seasonal flu virus that causes colds and flu. All of...

Senescence is a delayed state reached by damaged or aging cells, in which cells neither proliferate nor die. Senescent cells send informational signals to their surroundings to warn of their presence...

Influenza A Virus (IAV) is one of the most important causes of respiratory infections and has caused tens of millions of deaths in several pandemic outbreaks throughout human history. In recent years...

T2DM is a complex endocrine and metabolic disease with a heterogeneous pathology characterized by the interaction of genetic and environmental factors, as well as varying degrees of insulin resistance...