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Inhibition of Ctbp Complex and Fbxo11 Enhances Mhc Class Ii Expression and Antitumor Immune Response

Acute myeloid leukemia (AML) is a clonal malignant proliferative disease of the hematopoietic system's myeloid primitive cells that is highly heterogeneous, usually incurable with chemotherapy, has a...

Jerry Carter Dec 19, 2022
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Smoking is a Major Risk Factor for Colorectal Cancer (Crc)

Yu Jun's team from The Chinese University of Hong Kong published a paper in Gut (IF=32) titled "Cigarette smoke promotes colorectal cancer through modulation of gut microbiota and related metabolites...

Jerry Carter Dec 19, 2022
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Mapk4 May Serve As a Novel Therapeutic Target for Human Triple-Negative Breast Cancer

There is mounting evidence that the enzyme MAPK4 is involved in cancer growth and resistance to specific therapies. Researchers from Baylor College of Medicine and other institutions discovered that...

Jerry Carter Dec 19, 2022
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Senescent Cells Can Act As a Cancer Vaccine and Promote Anti-Tumor Immune Response After Inoculation

Senescence is a delayed state reached by damaged or aging cells, in which cells neither proliferate nor die. Senescent cells send informational signals to their surroundings to warn of their presence...

Jerry Carter Nov 29, 2022
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It's Horrible! a Bizarre Virus That Merges into One Has Been Discovered and is More Likely to Infect

Many serious diseases are caused by viruses, such as the new coronavirus that caused a global epidemic, the terrifying Ebola virus, and even the seasonal flu virus that causes colds and flu. All of...

Jerry Carter Nov 29, 2022
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Dissecting the Alternative Splicing Mechanism of Influenza Virus: a New Host-Targeted Antiviral Stra

Influenza A Virus (IAV) is one of the most important causes of respiratory infections and has caused tens of millions of deaths in several pandemic outbreaks throughout human history. In recent years...

Jerry Carter Nov 29, 2022
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A Novel Mechanism of Thyroid Hormone Regulation of Glucose Homeostasis

T2DM is a complex endocrine and metabolic disease with a heterogeneous pathology characterized by the interaction of genetic and environmental factors, as well as varying degrees of insulin resistance...

Jerry Carter Nov 29, 2022
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Genomic Signature Drives Breast Cancer Treatment Decisions

Fabrice Andre's research group at the Gustave Roussy Oncology Department in France recently published the article "Genomics to select treatment for patients with metastatic breast cancer" in Nature...

Jerry Carter Nov 09, 2022
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Nano-Based in Situ Cancer Vaccine

Cancer immunotherapy has shown great promise in cancer treatment over the last decade. Several cancer immunotherapies, such as immune checkpoint blockade therapies, cancer vaccines, and CAR-T...

Jerry Carter Nov 09, 2022
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Chimpanzee Adenovirus + Self-Amplifying Mrna Cancer Vaccine Prolongs Overall Survival in Patients WI

With the advancement of biology and medicine, scientists have gained a better understanding of cancer and our own immune system, and they have realized that the immune system is the most lethal weapon...

Jerry Carter Nov 09, 2022
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Rheumatoid Arthritis Drug Kinnopin Reduces Leptin Levels and Exerts Anti-Diabetic Effects

Recently, Sean M. Hartig's team from Baylor College of Medicine published an article in Cell Metabolism titled "The rheumatoid arthritis drug auranofin lowers leptin levels and exerts antidiabetic...

Jerry Carter Nov 09, 2022
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A Newly Developed Hydrogel Platform Loaded with Rna-Liposome Nanoparticle Drugs for the Treatment Of

Pancreatic cancer is a highly malignant tumor of the digestive system, and traditional clinical treatments such as surgery and chemotherapy are very limited in terms of prolonging the survival cycle...

Jerry Carter Nov 09, 2022
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Aerobic Exercise Reprograms the Immune System and Enhances Anti-Tumor Immunity

Pancreatic cancer (PC) is a highly malignant digestive tract tumor that is difficult to diagnose and treat, with pancreatic ductal adenocarcinoma (PDAC) accounting for more than 95% of all pancreatic...

Jerry Carter Nov 09, 2022
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Cancer Vaccines Are the Next Frontier in Immunotherapy

While traditional vaccines are dedicated to the prevention of a wide range of infectious diseases, cancer vaccines, which have received much attention in recent years, aim to focus the power of the...

Jerry Carter Oct 23, 2022
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A New Study Suggests Hemorrhagic Fever in Apes May Spread to Humans

In a new study, researchers have found that an unknown family of viruses has become endemic in wild African primates and causes fatal Ebola-like symptoms in some monkeys, and is poised to infect...

Jerry Carter Oct 23, 2022
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