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Heat shock protein 90 (HSP90), a molecular target for cancer, has a history of more than 10 years. HSP90 is one of the most active chaperone proteins in cell, which not only involves in the folding...

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Long-term, localized delivery of small molecules from a biodegradable thin film is challenging owing to their low molecular weight and poor charge density. While MIT researchers recently developed a...

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Synta Pharmaceuticals Corp. announced the advancement of ganetespib into the Phase 3 extension of the AML LI-1 trial. AML LI-1 is a multicenter, randomized Phase 2/3 clinical study evaluating several...

Joshi and co-workers show in this research article data suggesting that Golgi is a potential drug target for AD. In this study, APPswe/PS1?E9, a widely used AD transgenic mouse model was utilized...