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Statins show promise in solving small cell lung cancer (SCLC) chemoresistance problemSCLC, which accounts for around 15% of lung cancers, is the most aggressive and has the worst prognosis of all lung...
A pneumonia epidemic caused by the new coronavirus SARS-CoV-2 in early 2020 triggered a global pandemic that has lasted to this day. Unfortunately, the situation with the epidemic remains dire to this...
Although recently overshadowed by the global epidemic of COVID-19, humanity is still facing an epidemic of another disease, HIV/AIDS, with approximately 38 million people living with HIV worldwide...
The continued emergence of SARS-CoV-2 variants and breakthrough infections following vaccination underscore the need to study the effectiveness of current COVID-19 vaccines in the real world.To date...
On March 31, Immutep announced that its LAG-3 fusion protein eftilagimod alpha (Efti, also known as IMP321), in combination with MSD's heavyweight PD-1 inhibitor Keytruda, has yielded positive interim...
Genotoxic Cancer Therapy (GCT) kills cancer cells by causing extensive DNA damage. Among them, Radiation therapy (RT) is the most widely used genotoxic cancer therapy. When radiation passes through...
Life is all about working out. Moderate exercise not only strengthens the body, but also improves the metabolic state and slows the progression of diseases. However, different times of exercise may...
On March 19, Bristol-Myers Squibb (BMS) announced that its dual immunotherapy combination Opdualag had received accelerated marketing approval from the FDA. Opdualag therapy is a fixed-dose...
BackgroundTumor immunotherapies compose immune checkpoint inhibitors, therapeutic antibodies, tumor vaccines, cellular therapies, and so on. However, each has its own set of issues, such as the fact...
Glycosylation is a sophisticated type of post-translational modification that impacts over 50% of cellular proteins and is a critical regulator of
Silence Therapeutics, a pioneer in the development of novel small interfering RNA (siRNA) therapeutics, and Mallinckrodt plc, a global biopharmaceutical company, announced the submission of a clinical...
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) are adult-onset progressive neurodegenerative diseases that belong to the same disease spectrum. In ALS, the motor...
Despite being recently covered by the global epidemic of COVID-19, humanity is still facing an epidemic of another disease, AIDS, with approximately 38 million people living with
Pancreatic cancer is a highly malignant tumor of the digestive tract that is difficult to diagnose and treat, and the morbidity and mortality rates have risen dramatically in recent years. Pancreatic...
Targeting B cells in T1DB cells have also been associated with the development of T1D. In animal models, B-cell deficiency or absence inhibits the development of diabetes mellitus. In addition, B...