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Despite being recently covered by the global epidemic of COVID-19, humanity is still facing an epidemic of another disease, AIDS, with approximately 38 million people living with
Pancreatic cancer is a highly malignant tumor of the digestive tract that is difficult to diagnose and treat, and the morbidity and mortality rates have risen dramatically in recent years. Pancreatic...
Targeting B cells in T1DB cells have also been associated with the development of T1D. In animal models, B-cell deficiency or absence inhibits the development of diabetes mellitus. In addition, B...
Novel cytotoxic drugsNew cytotoxic drugs have been developed to target cancer cells with low antigen expression or resistance to auristatins or maytansinoids. For this purpose, PBD dimers have been...
Kadcyla and second-generation non-cleavable linkersAlternative linker design methodologies are still under development. Immunogen discovered a very powerful ADC by an accidental discovery. The lysine...
As the COVID-19 pandemic enters its third year, efforts to mitigate the risk of infection remain critical, especially for vulnerable populations.Recently, Andrea Edlow et al. of Massachusetts General...
Safe and effective systemic delivery of mRNA to specific organs and cells in vivo remains a major challenge in the development of mRNA-based therapies. Currently, the application of mRNA-based...
Omicron, as the most transmissible variant of SARS-CoV-2, is rapidly spreading over the world and has displaced Delta as the dominant strain in a number of regions. Some experts have indicated that...
Type 1 diabetes (T1D) is a complex T-cell-mediated autoimmune disease that results in the destruction of insulin-producing beta cells and inadequate insulin secretion. Prior to the discovery of...
At an academic conference on Feb 15, U.S. experts announced the world's first female AIDS "cure," making it the third case of HIV infection to be cured. After therapy and withdrawal of antiviral...
"A neuronal mechanism for motivational control of behavior" published in Science by Friedrich Miescher Institute for Biomedical Research, University of Basel.Almost everything you do in your daily...
Immunotherapy, in addition to surgery, chemotherapy, and radiotherapy, has now become the fourth pillar of anticancer treatment, with T cell-based immunotherapy being a successful cancer treatment...
Recent research has uncovered an especially aggressive mechanism for the spread of a particularly aggressive type of breast cancer, in which the NUP93 protein plays a key role. Because
Antibody-drug conjugate (ADC), a compound that connects a cytotoxic small-molecule drug to a monoclonal antibody via a rationally established linker, which selectively delivers an efficient cytotoxic...
Newsmax Media, Inc., or Newsmax, is a multimedia broadcasting and digital publishing company founded in 1998. The company has been thriving for more than two decades, focusing on providing information...