Sugar is a direct source of sweetness that not only enhances the flavor of food but also serves as a source of energy for the body. Sugar is used in everyday life to give us a "sweet" feeling, whether...

January 6, 2022—Researchers at the Perelman School of Medicine at the University of Pennsylvania published a research paper in Science titled: CAR-T cells produced in vivo to treat cardiac...

The vascular endothelium is a single layer of endothelial cells that lines the surface of the vascular lumen, and it plays an important role in maintaining vascular homeostasis and tissue fluid...

Published by Vijay K Singh and Thomas M Seed on September 3, 2021, in Expert Opinion on Drug Discovery and deals with the necessity of animal models for modern drug research in the direction of animal...

Vaccines are an unparalleled medical milestone that has saved countless lives by harnessing the human immune system, according to the history of human development. Vaccine remains the most effective...

Since they were originally explored in animal models in the 1960s, antibody-drug conjugates (ADCs) have seen many booms. The initial ADC clinical studies took place in the 1980s, and Mylotarg, the...

Researchers at the University of Helsinki have devised a new technique for returning human cells to a stem cell state that is faster and more reliable. Pluripotent stem cells, which can differentiate...

A review paper was published in the journal Nature Reviews Drug Discovery on January 13, 2022: Despite the fact that the familiar "-mab" has retired, it marks a new era in antibody drug development.In...

"Intratumourally injected alum-tethered cytokines elicit potent and safer local and systemic anticancer immunity", published by a team of researchers from the Massachusetts Institute of Technology...

The use of immune checkpoint inhibitors (ICIs) has become the most important achievement in oncology in the last decade. From a more holistic viewpoint, it is a powerful clinical strategy.Cancer cells...

"Coordinated post-transcriptional modulation of oncogene-induced senescence by UNR/CSDE1," according to a study published in Cell Reports (Jan. 11), shows an important molecular mechanism that...

NKG2A (NK cell lectin-like receptor subfamily C member 1)Molecular Alias: NKG2A, CD159a, KLRC1, NK cell receptor ABackground:NKG2A/B/C/D/E/F are members of the natural killer cell receptor family2...

The haze of the COVID-19 epidemic still hangs over human society and has yet to subside. As the northern hemisphere enters the cold season and a new mutant strain of Omicron emerges, a new wave of...

N-chain protein glycosylation in the brain is an understudied aspect of glucose utilization that affects a variety of cellular processes, including resting membrane potential, axonal activation, and...

Immunotherapy has been successfully applied clinically to treat a wide range of hematological and solid metastatic malignancies. The most widely used drugs targeting immune checkpoint