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Immunometabolism involves glycolysis, tricarboxylic acid cycle, and pentose phosphate pathway and amino acid metabolism and other intracellular metabolic pathways, which play a vital role in...
Take care of your health with primary care physicians in Laurel MD!It’s very important to select a new primary care doctor especially when you get older because you do not always feel comfortable with...
Zika virus (ZIKV) is a new acute viral infectious disease mainly transmitted by Aedes mosquitoes. The clinical manifestations are usually mild, but some cases may develop serious symptoms such as...
Influenza is a respiratory infectious disease caused by the influenza virus. About 5% to 10% of people in the world are infected with influenza every year. According to the scale, influenza epidemics...
PDX model (full name: patient-derived tumor xenograft model) is a transplanted tumor model formed by implanting patient-derived tumor tissue and primary cells into the body of immunodeficient mice. It...
A few days ago, Arvinas, which is committed to developing targeted protein degradation therapies, announced at the American Association for Cancer Research (AACR) annual meeting the molecular...
A huge population consume large amounts of ready-to-eat foods such as bread, biscuits, and various snacks every day, which have been highly or overly heat-processed. During the processing, the...
Podiatrists treat a wide range of foot problems and different types of people. There are many factors that are impacting on the demand for services and almost all of them are increasing or are...
Hepatitis B virus (HBV) infection is the leading cause of global morbidity and mortality. The WHO estimates that approximately 20 million people worldwide are infected with HBV. Among those...
In the process of preclinical development, a compound or biological agent must go through the testing phases, for the following targets, which are the identification of potential targets of disease...
PROTAC is a novel type of drug that is different from antibodies and traditional small molecule inhibitors, consisting of a linker and two warheads. One end of the PROTAC molecule binds to the target...
Researchers such as Mansun Law of The Scripps Research Institute discovered that rhesus monkeys can produce a convergent antibody response to HCV envelope glycoprotein. The paper entitled "Functional...
Phage display technology is a powerful gene expression screening technology, which was first described by SmithMl et al. in Science in 1985. The basic principle is to clone the gene of the foreign...
10 ADC drugs have been approved by the FDA for the treatment of various cancers including hematological tumors and solid tumors in a decade since 2010. Of the 10 ADC drugs currently on the market, 7...
Penicillin is an important antibiotic with high efficiency, low toxicity, and wide clinical application. At the beginning of the 20th century, there were no drug to treat bacterial infections with low...