Zhang Qing

As commonly known in the biomedical community, genetic and epigenetic alterations are regarded as biomarkers for cancer detection, while some scientist looked for new candidates to indentify cancer...

STAT transcription factor involved in many kinds of cancers. STAT3 is usually in a state of activation in tumor cells, therefore drug targeting effect of STAT3 is often used in cancer treatment...

Mendel’s 1860s pioneering studies of pea plant crosses and breeding is a symbol of the foundation of modern inheritance mechanisms. As we know, DNA is the main carrier of genetic information from one...

A new research indicated that the treatment with poly (ADP-ribose) polymerase (PARP) inhibitors, together with chemotherapy drugs, could be applied for RUNX leukemia. This study was published in Cell...

Tumor recurrence is regarded as the biggest predicament in cancer therapeutics: tumors did not respond to chemotherapy anymore because they are resistant to these chemical compounds. In some cases...

Hepatocellular carcinoma (HCC) is a prototype of inflammation-associated cancer. Oncoprotein Gankyrin, mostly increases in HCC, plays a critical role in HCC development and metastasis. However, the...

Consequently, conditions causing switch while in the equilibrium between phosphorylated and no-phosphorylated says can dictate the functionality of a protein and hereafter the cells fate.Protein...

Epigenetic regulation, including DNA methylation, histone modifications, and chromatin remodeling, play an important role in the nervous system. However, the role of epigenetic mechanisms contribute...

Cell division and differentiation of lymphocytes Today, I am reading a great review article about T cell division and differentiation. So like to share it here. Adaptive immunity requires the...

In this Nature review article, Dr. Wells and Dr. Morawski demonstrated that CDKs play important roles in driving specific transcriptional programmes involved in T cell differentiation and function...

Ovarian cancer is the most deadly cancer in female gynecological diseases, studies have shown that a woman's chance of about 50% in the period of their life will suffer from the disease, researchers...

Many advanced cancer patients die from a state called cachexia which is the result of the interaction between the host and the tumor and mainly displayed by the weight loss in short time, malnutrition...

It would be appealing to speculate that the mixture of a a mainstream treatment and a senescence induced therapy may cooperate to entirely remove cancer. p53, an important growth suppressor or...

Breast cancer is heterogeneous in genetic composition. To improve treatments for this disease, Scientists have developed a classification system called IntClust that classifies it into 10 different...

Startup bio-pharma companies are extremely over-valued in term ofstock price, simply because of the potential investment return from success of their clinical trials. Once these trials fail, the...